Takuwa Y - Search Results

1

Antiproliferative property of sphingosine 1-phosphate in rat hepatocytes involves activation of Rho via Edg-5.

Ikeda H, Satoh H, Yanase M, Inoue Y, Tomiya T, Arai M, Tejima K, Nagashima K, Maekawa H, Yahagi N, Yatomi Y, Sakurada S, Takuwa Y, Ogata I, Kimura S, Fujiwara K. Ikeda H, et al. Among authors: takuwa y. Gastroenterology. 2003 Feb;124(2):459-69. doi: 10.1053/gast.2003.50049. Gastroenterology. 2003. PMID: 12557151

2

Biological activities of novel lipid mediator sphingosine 1-phosphate in rat hepatic stellate cells.

Ikeda H, Yatomi Y, Yanase M, Satoh H, Maekawa H, Ogata I, Ozaki Y, Takuwa Y, Mochida S, Fujiwara K. Ikeda H, et al. Among authors: takuwa y. Am J Physiol Gastrointest Liver Physiol. 2000 Aug;279(2):G304-10. doi: 10.1152/ajpgi.2000.279.2.G304. Am J Physiol Gastrointest Liver Physiol. 2000. PMID: 10915638 Free article.

3

Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents.

Kageyama Y, Ikeda H, Watanabe N, Nagamine M, Kusumoto Y, Yashiro M, Satoh Y, Shimosawa T, Shinozaki K, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Yokota H, Koyama T, Ishimaru K, Okamoto Y, Takuwa Y, Koike K, Yatomi Y. Kageyama Y, et al. Among authors: takuwa y. Hepatology. 2012 Oct;56(4):1427-38. doi: 10.1002/hep.25780. Hepatology. 2012. PMID: 22505286

4

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases.

Takuwa Y, Ikeda H, Okamoto Y, Takuwa N, Yoshioka K. Takuwa Y, et al. Among authors: takuwa n. Biochim Biophys Acta. 2013 Jan;1831(1):185-92. doi: 10.1016/j.bbalip.2012.06.008. Epub 2012 Jun 23. Biochim Biophys Acta. 2013. PMID: 22735357 Free article. Review.

5

Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator.

Takuwa Y, Okamoto H, Takuwa N, Gonda K, Sugimoto N, Sakurada S. Takuwa Y, et al. Among authors: takuwa n. Mol Cell Endocrinol. 2001 May 25;177(1-2):3-11. doi: 10.1016/s0303-7207(01)00441-5. Mol Cell Endocrinol. 2001. PMID: 11377814 Review.

6

Sphingosine 1-phosphate receptor expression profile in human gastric cancer cells: differential regulation on the migration and proliferation.

Yamashita H, Kitayama J, Shida D, Yamaguchi H, Mori K, Osada M, Aoki S, Yatomi Y, Takuwa Y, Nagawa H. Yamashita H, et al. Among authors: takuwa y. J Surg Res. 2006 Jan;130(1):80-7. doi: 10.1016/j.jss.2005.08.004. Epub 2005 Sep 23. J Surg Res. 2006. PMID: 16183075

7

EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibition.

Okamoto H, Takuwa N, Gonda K, Okazaki H, Chang K, Yatomi Y, Shigematsu H, Takuwa Y. Okamoto H, et al. Among authors: takuwa y, takuwa n. J Biol Chem. 1998 Oct 16;273(42):27104-10. doi: 10.1074/jbc.273.42.27104. J Biol Chem. 1998. PMID: 9765227 Free article.

8

The novel sphingosine 1-phosphate receptor AGR16 is coupled via pertussis toxin-sensitive and -insensitive G-proteins to multiple signalling pathways.

Gonda K, Okamoto H, Takuwa N, Yatomi Y, Okazaki H, Sakurai T, Kimura S, Sillard R, Harii K, Takuwa Y. Gonda K, et al. Among authors: takuwa y, takuwa n. Biochem J. 1999 Jan 1;337 ( Pt 1)(Pt 1):67-75. Biochem J. 1999. PMID: 9854026 Free PMC article.

9

Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3.

Okamoto H, Takuwa N, Yokomizo T, Sugimoto N, Sakurada S, Shigematsu H, Takuwa Y. Okamoto H, et al. Among authors: takuwa y, takuwa n. Mol Cell Biol. 2000 Dec;20(24):9247-61. doi: 10.1128/MCB.20.24.9247-9261.2000. Mol Cell Biol. 2000. PMID: 11094076 Free PMC article.

10

Thrombin activates two stress-activated protein kinases, c-Jun N-terminal kinase and p38, in HepG2 cells.

Mitsui H, Maruyama T, Kimura S, Takuwa Y. Mitsui H, et al. Among authors: takuwa y. Hepatology. 1998 May;27(5):1362-7. doi: 10.1002/hep.510270524. Hepatology. 1998. PMID: 9581692

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