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Blood levels of transforming growth factor-beta 1 (TGF-beta1) are elevated in both relapsing remitting and chronic progressive multiple sclerosis (MS) patients and are further augmented by treatment with interferon-beta 1b (IFN-beta1b).
Nicoletti F, Di Marco R, Patti F, Reggio E, Nicoletti A, Zaccone P, Stivala F, Meroni PL, Reggio A. Nicoletti F, et al. Among authors: reggio a, reggio e. Clin Exp Immunol. 1998 Jul;113(1):96-9. doi: 10.1046/j.1365-2249.1998.00604.x. Clin Exp Immunol. 1998. PMID: 9697990 Free PMC article. Clinical Trial.
Short-term treatment of relapsing remitting multiple sclerosis patients with interferon (IFN)-beta1B transiently increases the blood levels of interleukin (IL)-6, IL-10 and IFN-gamma without significantly modifying those of IL-1beta, IL-2, IL-4 and tumour necrosis factor-alpha.
Nicoletti F, Di Marco R, Patti F, Zaccone P, L'Episcopo MR, Reggio E, Xiang M, Nicoletti A, Reggio A. Nicoletti F, et al. Among authors: reggio a, reggio e. Cytokine. 2000 Jun;12(6):682-7. doi: 10.1006/cyto.1999.0616. Cytokine. 2000. PMID: 10843745
The antiinflammatory cytokine interleukin-13 is not detectable in the circulation of multiple sclerosis patients and is not inducible by interferon-beta1b treatment, that neither modifies its ex vivo secretion from peripheral blood mononuclear cells.
Nicoletti F, Di Marco R, Patti F, Nicoletti A, Leonardi C, Reggio E, Meroni P, Reggio A. Nicoletti F, et al. Among authors: reggio a, reggio e. Autoimmunity. 2000 Dec;32(4):265-70. doi: 10.3109/08916930008994100. Autoimmunity. 2000. PMID: 11191285 Free article.
[Spasticity in multiple sclerosis].
Pappalardo A, Patti F, Reggio A, Guglielmino A, Mangiameli S. Pappalardo A, et al. Among authors: reggio a. Clin Ter. 2004 Apr;155(4):135-8. Clin Ter. 2004. PMID: 15354762 Review. Italian.
134 results