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Processing and function of CFTR-DeltaF508 are species-dependent.
Ostedgaard LS, Rogers CS, Dong Q, Randak CO, Vermeer DW, Rokhlina T, Karp PH, Welsh MJ. Ostedgaard LS, et al. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15370-5. doi: 10.1073/pnas.0706974104. Epub 2007 Sep 14. Proc Natl Acad Sci U S A. 2007. PMID: 17873061 Free PMC article.
CFTR-deficient pigs display peripheral nervous system defects at birth.
Reznikov LR, Dong Q, Chen JH, Moninger TO, Park JM, Zhang Y, Du J, Hildebrand MS, Smith RJ, Randak CO, Stoltz DA, Welsh MJ. Reznikov LR, et al. Among authors: randak co. Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3083-8. doi: 10.1073/pnas.1222729110. Epub 2013 Feb 4. Proc Natl Acad Sci U S A. 2013. PMID: 23382208 Free PMC article.
Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function in Primary Human Airway Epithelia.
Dong Q, Ernst SE, Ostedgaard LS, Shah VS, Ver Heul AR, Welsh MJ, Randak CO. Dong Q, et al. Among authors: randak co. J Biol Chem. 2015 May 29;290(22):14140-53. doi: 10.1074/jbc.M114.611616. Epub 2015 Apr 17. J Biol Chem. 2015. PMID: 25887396 Free PMC article.
CFTR with a partially deleted R domain corrects the cystic fibrosis chloride transport defect in human airway epithelia in vitro and in mouse nasal mucosa in vivo.
Ostedgaard LS, Zabner J, Vermeer DW, Rokhlina T, Karp PH, Stecenko AA, Randak C, Welsh MJ. Ostedgaard LS, et al. Among authors: randak c. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3093-8. doi: 10.1073/pnas.261714599. Epub 2002 Feb 19. Proc Natl Acad Sci U S A. 2002. PMID: 11854474 Free PMC article.
27 results