Villeneuve L - Search Results

1

The UDP-glucuronosyltransferase 1A9 enzyme is a peroxisome proliferator-activated receptor alpha and gamma target gene.

Barbier O, Villeneuve L, Bocher V, Fontaine C, Torra IP, Duhem C, Kosykh V, Fruchart JC, Guillemette C, Staels B. Barbier O, et al. Among authors: villeneuve l. J Biol Chem. 2003 Apr 18;278(16):13975-83. doi: 10.1074/jbc.M300749200. Epub 2003 Feb 11. J Biol Chem. 2003. PMID: 12582161 Free article.

2

Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.

Villeneuve L, Girard H, Fortier LC, Gagné JF, Guillemette C. Villeneuve L, et al. J Pharmacol Exp Ther. 2003 Oct;307(1):117-28. doi: 10.1124/jpet.103.054072. Epub 2003 Aug 27. J Pharmacol Exp Ther. 2003. PMID: 12944498

3

Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.

Girard H, Court MH, Bernard O, Fortier LC, Villeneuve L, Hao Q, Greenblatt DJ, von Moltke LL, Perussed L, Guillemette C. Girard H, et al. Among authors: villeneuve l. Pharmacogenetics. 2004 Aug;14(8):501-15. doi: 10.1097/01.fpc.0000114754.08559.27. Pharmacogenetics. 2004. PMID: 15284532

4

Hepatic expression of the UGT1A9 gene is governed by hepatocyte nuclear factor 4alpha.

Barbier O, Girard H, Inoue Y, Duez H, Villeneuve L, Kamiya A, Fruchart JC, Guillemette C, Gonzalez FJ, Staels B. Barbier O, et al. Among authors: villeneuve l. Mol Pharmacol. 2005 Jan;67(1):241-9. doi: 10.1124/mol.104.003863. Epub 2004 Oct 6. Mol Pharmacol. 2005. PMID: 15470081

5

UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver.

Girard H, Thibaudeau J, Court MH, Fortier LC, Villeneuve L, Caron P, Hao Q, von Moltke LL, Greenblatt DJ, Guillemette C. Girard H, et al. Among authors: villeneuve l. Hepatology. 2005 Aug;42(2):448-57. doi: 10.1002/hep.20770. Hepatology. 2005. PMID: 15986396

6

Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer.

Gagnon JF, Bernard O, Villeneuve L, Têtu B, Guillemette C. Gagnon JF, et al. Among authors: villeneuve l. Clin Cancer Res. 2006 Mar 15;12(6):1850-8. doi: 10.1158/1078-0432.CCR-05-2130. Clin Cancer Res. 2006. PMID: 16551870

7

The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver.

Girard H, Villeneuve L, Court MH, Fortier LC, Caron P, Hao Q, von Moltke LL, Greenblatt DJ, Guillemette C. Girard H, et al. Among authors: villeneuve l. Drug Metab Dispos. 2006 Jul;34(7):1220-8. doi: 10.1124/dmd.106.009787. Epub 2006 Apr 4. Drug Metab Dispos. 2006. PMID: 16595709

8

UGT1A1 and UGT1A9 functional variants, meat intake, and colon cancer, among Caucasians and African-Americans.

Girard H, Butler LM, Villeneuve L, Millikan RC, Sinha R, Sandler RS, Guillemette C. Girard H, et al. Among authors: villeneuve l. Mutat Res. 2008 Sep 26;644(1-2):56-63. doi: 10.1016/j.mrfmmm.2008.07.002. Epub 2008 Jul 16. Mutat Res. 2008. PMID: 18675828 Free PMC article.

9

Deferiprone glucuronidation by human tissues and recombinant UDP glucuronosyltransferase 1A6: an in vitro investigation of genetic and splice variants.

Benoit-Biancamano MO, Connelly J, Villeneuve L, Caron P, Guillemette C. Benoit-Biancamano MO, et al. Among authors: villeneuve l. Drug Metab Dispos. 2009 Feb;37(2):322-9. doi: 10.1124/dmd.108.023101. Epub 2008 Oct 29. Drug Metab Dispos. 2009. PMID: 18971318

10

Genetic variations in UGT1A1 and UGT2B7 and endometrial cancer risk.

McGrath M, Lepine J, Lee IM, Villeneuve L, Buring J, Guillemette C, De Vivo I. McGrath M, et al. Among authors: villeneuve l. Pharmacogenet Genomics. 2009 Mar;19(3):239-43. doi: 10.1097/FPC.0b013e328323f66c. Pharmacogenet Genomics. 2009. PMID: 19352303 Free PMC article.

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