Gustafsson D - Search Results

1

Absorption, distribution, metabolism, and excretion of ximelagatran, an oral direct thrombin inhibitor, in rats, dogs, and humans.

Eriksson UG, Bredberg U, Hoffmann KJ, Thuresson A, Gabrielsson M, Ericsson H, Ahnoff M, Gislén K, Fager G, Gustafsson D. Eriksson UG, et al. Among authors: gustafsson d. Drug Metab Dispos. 2003 Mar;31(3):294-305. doi: 10.1124/dmd.31.3.294. Drug Metab Dispos. 2003. PMID: 12584156

2

A dose-ranging study of the oral direct thrombin inhibitor, ximelagatran, and its subcutaneous form, melagatran, compared with dalteparin in the prophylaxis of thromboembolism after hip or knee replacement: METHRO I. MElagatran for THRombin inhibition in Orthopaedic surgery.

Eriksson BI, Arfwidsson AC, Frison L, Eriksson UG, Bylock A, Kälebo P, Fager G, Gustafsson D. Eriksson BI, et al. Among authors: gustafsson d. Thromb Haemost. 2002 Feb;87(2):231-7. Thromb Haemost. 2002. PMID: 11858482 Clinical Trial.

3

Inhibition of thrombin generation by the oral direct thrombin inhibitor ximelagatran in shed blood from healthy male subjects.

Sarich TC, Eriksson UG, Mattsson C, Wolzt M, Frison L, Fager G, Gustafsson D. Sarich TC, et al. Among authors: gustafsson d. Thromb Haemost. 2002 Feb;87(2):300-5. Thromb Haemost. 2002. PMID: 11858491 Clinical Trial.

4

Effects of ximelagatran, an oral direct thrombin inhibitor, r-hirudin and enoxaparin on thrombin generation and platelet activation in healthy male subjects.

Sarich TC, Wolzt M, Eriksson UG, Mattsson C, Schmidt A, Elg S, Andersson M, Wollbratt M, Fager G, Gustafsson D. Sarich TC, et al. Among authors: gustafsson d. J Am Coll Cardiol. 2003 Feb 19;41(4):557-64. doi: 10.1016/s0735-1097(02)02868-1. J Am Coll Cardiol. 2003. PMID: 12598065 Free article. Clinical Trial.

5

Influence of age on the pharmacokinetics and pharmacodynamics of ximelagatran, an oral direct thrombin inhibitor.

Johansson LC, Frison L, Logren U, Fager G, Gustafsson D, Eriksson UG. Johansson LC, et al. Among authors: gustafsson d. Clin Pharmacokinet. 2003;42(4):381-92. doi: 10.2165/00003088-200342040-00006. Clin Pharmacokinet. 2003. PMID: 12648028 Clinical Trial.

6

No influence of ethnic origin on the pharmacokinetics and pharmacodynamics of melagatran following oral administration of ximelagatran, a novel oral direct thrombin inhibitor, to healthy male volunteers.

Johansson LC, Andersson M, Fager G, Gustafsson D, Eriksson UG. Johansson LC, et al. Among authors: gustafsson d. Clin Pharmacokinet. 2003;42(5):475-84. doi: 10.2165/00003088-200342050-00005. Clin Pharmacokinet. 2003. PMID: 12739985 Clinical Trial.

7

Pharmacokinetics and pharmacodynamics of ximelagatran, a novel oral direct thrombin inhibitor, in young healthy male subjects.

Eriksson UG, Bredberg U, Gislén K, Johansson LC, Frison L, Ahnoff M, Gustafsson D. Eriksson UG, et al. Among authors: gustafsson d. Eur J Clin Pharmacol. 2003 May;59(1):35-43. doi: 10.1007/s00228-003-0565-7. Epub 2003 Mar 27. Eur J Clin Pharmacol. 2003. PMID: 12743672 Clinical Trial.

8

The direct thrombin inhibitor melagatran and its oral prodrug H 376/95: intestinal absorption properties, biochemical and pharmacodynamic effects.

Gustafsson D, Nyström J, Carlsson S, Bredberg U, Eriksson U, Gyzander E, Elg M, Antonsson T, Hoffmann K, Ungell A, Sörensen H, Någård S, Abrahamsson A, Bylund R. Gustafsson D, et al. Thromb Res. 2001 Feb 1;101(3):171-81. doi: 10.1016/s0049-3848(00)00399-6. Thromb Res. 2001. PMID: 11228340

9

Pharmacokinetics of melagatran and the effect on ex vivo coagulation time in orthopaedic surgery patients receiving subcutaneous melagatran and oral ximelagatran: a population model analysis.

Eriksson UG, Mandema JW, Karlsson MO, Frison L, Gisleskog PO, Wählby U, Hamrén B, Gustafsson D, Eriksson BI. Eriksson UG, et al. Among authors: gustafsson d. Clin Pharmacokinet. 2003;42(7):687-701. doi: 10.2165/00003088-200342070-00006. Clin Pharmacokinet. 2003. PMID: 12844328 Clinical Trial.

10

A new oral anticoagulant: the 50-year challenge.

Gustafsson D, Bylund R, Antonsson T, Nilsson I, Nyström JE, Eriksson U, Bredberg U, Teger-Nilsson AC. Gustafsson D, et al. Nat Rev Drug Discov. 2004 Aug;3(8):649-59. doi: 10.1038/nrd1466. Nat Rev Drug Discov. 2004. PMID: 15286732 Review. No abstract available.

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