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Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage.
Yamamoto Y, Matsui J, Matsushima T, Obaishi H, Miyazaki K, Nakamura K, Tohyama O, Semba T, Yamaguchi A, Hoshi SS, Mimura F, Haneda T, Fukuda Y, Kamata JI, Takahashi K, Matsukura M, Wakabayashi T, Asada M, Nomoto KI, Watanabe T, Dezso Z, Yoshimatsu K, Funahashi Y, Tsuruoka A. Yamamoto Y, et al. Among authors: yoshimatsu k. Vasc Cell. 2014 Sep 6;6:18. doi: 10.1186/2045-824X-6-18. eCollection 2014. Vasc Cell. 2014. PMID: 25197551 Free PMC article.
Efficacy of oral E1210, a new broad-spectrum antifungal with a novel mechanism of action, in murine models of candidiasis, aspergillosis, and fusariosis.
Hata K, Horii T, Miyazaki M, Watanabe NA, Okubo M, Sonoda J, Nakamoto K, Tanaka K, Shirotori S, Murai N, Inoue S, Matsukura M, Abe S, Yoshimatsu K, Asada M. Hata K, et al. Among authors: yoshimatsu k. Antimicrob Agents Chemother. 2011 Oct;55(10):4543-51. doi: 10.1128/AAC.00366-11. Epub 2011 Jul 25. Antimicrob Agents Chemother. 2011. PMID: 21788462 Free PMC article.
In vitro activity of E1210, a novel antifungal, against clinically important yeasts and molds.
Miyazaki M, Horii T, Hata K, Watanabe NA, Nakamoto K, Tanaka K, Shirotori S, Murai N, Inoue S, Matsukura M, Abe S, Yoshimatsu K, Asada M. Miyazaki M, et al. Among authors: yoshimatsu k. Antimicrob Agents Chemother. 2011 Oct;55(10):4652-8. doi: 10.1128/AAC.00291-11. Epub 2011 Aug 8. Antimicrob Agents Chemother. 2011. PMID: 21825291 Free PMC article.
602 results