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Increased anxiety in corticotropin-releasing factor type 2 receptor-null mice requires recent acute stress exposure and is associated with dysregulated serotonergic activity in limbic brain areas.
Issler O, Carter RN, Paul ED, Kelly PA, Olverman HJ, Neufeld-Cohen A, Kuperman Y, Lowry CA, Seckl JR, Chen A, Jamieson PM. Issler O, et al. Among authors: kelly pa. Biol Mood Anxiety Disord. 2014 Jan 21;4(1):1. doi: 10.1186/2045-5380-4-1. Biol Mood Anxiety Disord. 2014. PMID: 24447313 Free PMC article.
Chronic activation of corticotropin-releasing factor type 2 receptors reveals a key role for 5-HT1A receptor responsiveness in mediating behavioral and serotonergic responses to stressful challenge.
Neufeld-Cohen A, Kelly PA, Paul ED, Carter RN, Skinner E, Olverman HJ, Vaughan JM, Issler O, Kuperman Y, Lowry CA, Vale WW, Seckl JR, Chen A, Jamieson PM. Neufeld-Cohen A, et al. Among authors: kelly pa. Biol Psychiatry. 2012 Sep 15;72(6):437-47. doi: 10.1016/j.biopsych.2012.05.005. Epub 2012 Jun 15. Biol Psychiatry. 2012. PMID: 22704666 Free PMC article.
623 results