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Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta.
Boyd JD, Jang H, Shepherd KR, Faherty C, Slack S, Jiao Y, Smeyne RJ. Boyd JD, et al. Among authors: smeyne rj. Brain Res. 2007 Oct 17;1175:107-16. doi: 10.1016/j.brainres.2007.07.067. Epub 2007 Aug 9. Brain Res. 2007. PMID: 17884023 Free PMC article.
Exercise protects against MPTP-induced neurotoxicity in mice.
Gerecke KM, Jiao Y, Pani A, Pagala V, Smeyne RJ. Gerecke KM, et al. Among authors: smeyne rj. Brain Res. 2010 Jun 23;1341:72-83. doi: 10.1016/j.brainres.2010.01.053. Epub 2010 Jan 29. Brain Res. 2010. PMID: 20116369 Free PMC article.
The MPTP model of Parkinson's disease.
Smeyne RJ, Jackson-Lewis V. Smeyne RJ, et al. Brain Res Mol Brain Res. 2005 Mar 24;134(1):57-66. doi: 10.1016/j.molbrainres.2004.09.017. Brain Res Mol Brain Res. 2005. PMID: 15790530 Review.
120 results