Nakaya K - Search Results

1

Beta-hydroxyisovalerylshikonin induces apoptosis in human leukemia cells by inhibiting the activity of a polo-like kinase 1 (PLK1).

Masuda Y, Nishida A, Hori K, Hirabayashi T, Kajimoto S, Nakajo S, Kondo T, Asaka M, Nakaya K. Masuda Y, et al. Among authors: nakaya k. Oncogene. 2003 Feb 20;22(7):1012-23. doi: 10.1038/sj.onc.1206200. Oncogene. 2003. PMID: 12592388

2

Sophoranone, extracted from a traditional Chinese medicine Shan Dou Gen, induces apoptosis in human leukemia U937 cells via formation of reactive oxygen species and opening of mitochondrial permeability transition pores.

Kajimoto S, Takanashi N, Kajimoto T, Xu M, Cao J, Masuda Y, Aiuchi T, Nakajo S, Ida Y, Nakaya K. Kajimoto S, et al. Among authors: nakaya k. Int J Cancer. 2002 Jun 20;99(6):879-90. doi: 10.1002/ijc.10414. Int J Cancer. 2002. PMID: 12115492

3

Beta-hydroxyisovalerylshikonin is a novel and potent inhibitor of protein tyrosine kinases.

Hashimoto S, Xu Y, Masuda Y, Aiuchi T, Nakajo S, Uehara Y, Shibuya M, Yamori T, Nakaya K. Hashimoto S, et al. Among authors: nakaya k. Jpn J Cancer Res. 2002 Aug;93(8):944-51. doi: 10.1111/j.1349-7006.2002.tb01341.x. Jpn J Cancer Res. 2002. PMID: 12716473 Free PMC article.

4

Beta-hydroxyisovalerylshikonin and cisplatin act synergistically to inhibit growth and to induce apoptosis of human lung cancer DMS114 cells via a tyrosine kinase-dependent pathway.

Xu Y, Kajimoto S, Nakajo S, Nakaya K. Xu Y, et al. Among authors: nakaya k. Oncology. 2004;66(1):67-75. doi: 10.1159/000076337. Oncology. 2004. PMID: 15031601

5

Involvement of tumor necrosis factor receptor-associated protein 1 (TRAP1) in apoptosis induced by beta-hydroxyisovalerylshikonin.

Masuda Y, Shima G, Aiuchi T, Horie M, Hori K, Nakajo S, Kajimoto S, Shibayama-Imazu T, Nakaya K. Masuda Y, et al. Among authors: nakaya k. J Biol Chem. 2004 Oct 8;279(41):42503-15. doi: 10.1074/jbc.M404256200. Epub 2004 Jul 28. J Biol Chem. 2004. PMID: 15292218 Free article.

6

A tyrosine kinase inhibitor, beta-hydroxyisovalerylshikonin, induced apoptosis in human lung cancer DMS114 cells through reduction of dUTP nucleotidohydrolase activity.

Kajimoto S, Horie M, Manabe H, Masuda Y, Shibayama-Imazu T, Nakajo S, Gong XF, Obama T, Itabe H, Nakaya K. Kajimoto S, et al. Among authors: nakaya k. Biochim Biophys Acta. 2008 Jan;1782(1):41-50. doi: 10.1016/j.bbadis.2007.11.004. Epub 2007 Nov 22. Biochim Biophys Acta. 2008. PMID: 18078828 Free article.

7

Bufalin induces apoptosis and influences the expression of apoptosis-related genes in human leukemia cells.

Masuda Y, Kawazoe N, Nakajo S, Yoshida T, Kuroiwa Y, Nakaya K. Masuda Y, et al. Among authors: nakaya k. Leuk Res. 1995 Aug;19(8):549-56. doi: 10.1016/0145-2126(95)00031-i. Leuk Res. 1995. PMID: 7658701

8

The cooperative interaction of two different signaling pathways in response to bufalin induces apoptosis in human leukemia U937 cells.

Watabe M, Masuda Y, Nakajo S, Yoshida T, Kuroiwa Y, Nakaya K. Watabe M, et al. Among authors: nakaya k. J Biol Chem. 1996 Jun 14;271(24):14067-72. doi: 10.1074/jbc.271.24.14067. J Biol Chem. 1996. PMID: 8662906 Free article.

9

Geranylgeraniol potently induces caspase-3-like activity during apoptosis in human leukemia U937 cells.

Masuda Y, Nakaya M, Nakajo S, Nakaya K. Masuda Y, et al. Among authors: nakaya m, nakaya k. Biochem Biophys Res Commun. 1997 May 29;234(3):641-5. doi: 10.1006/bbrc.1997.6690. Biochem Biophys Res Commun. 1997. PMID: 9175767

10

Bcl-2 protein inhibits bufalin-induced apoptosis through inhibition of mitogen-activated protein kinase activation in human leukemia U937 cells.

Watabe M, Kawazoe N, Masuda Y, Nakajo S, Nakaya K. Watabe M, et al. Among authors: nakaya k. Cancer Res. 1997 Aug 1;57(15):3097-100. Cancer Res. 1997. PMID: 9242431

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