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Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype.
Bavo F, Pallavicini M, Gotti C, Appiani R, Moretti M, Colombo SF, Pucci S, Viani P, Budriesi R, Renzi M, Fucile S, Bolchi C. Bavo F, et al. Among authors: renzi m. J Med Chem. 2020 Dec 24;63(24):15668-15692. doi: 10.1021/acs.jmedchem.0c01150. Epub 2020 Dec 16. J Med Chem. 2020. PMID: 33325696 Free article.
Evidence of a dual mechanism of action underlying the anti-proliferative and cytotoxic effects of ammonium-alkyloxy-stilbene-based α7- and α9-nicotinic ligands on glioblastoma cells.
Pucci S, Bolchi C, Bavo F, Pallavicini M, De Palma C, Renzi M, Fucile S, Benfante R, Di Lascio S, Lattuada D, Bessereau JL, D'Alessandro M, Risson V, Zoli M, Clementi F, Gotti C. Pucci S, et al. Among authors: renzi m. Pharmacol Res. 2022 Jan;175:105959. doi: 10.1016/j.phrs.2021.105959. Epub 2021 Oct 28. Pharmacol Res. 2022. PMID: 34756924 Free article.
247 results