Kersey JH - Search Results

1

Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.

Armstrong SA, Kung AL, Mabon ME, Silverman LB, Stam RW, Den Boer ML, Pieters R, Kersey JH, Sallan SE, Fletcher JA, Golub TR, Griffin JD, Korsmeyer SJ. Armstrong SA, et al. Among authors: kersey jh. Cancer Cell. 2003 Feb;3(2):173-83. doi: 10.1016/s1535-6108(03)00003-5. Cancer Cell. 2003. PMID: 12620411 Free article.

2

Malignant transformation initiated by Mll-AF9: gene dosage and critical target cells.

Chen W, Kumar AR, Hudson WA, Li Q, Wu B, Staggs RA, Lund EA, Sam TN, Kersey JH. Chen W, et al. Among authors: kersey jh. Cancer Cell. 2008 May;13(5):432-40. doi: 10.1016/j.ccr.2008.03.005. Cancer Cell. 2008. PMID: 18455126 Free PMC article.

3

EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.

Bindels EM, Havermans M, Lugthart S, Erpelinck C, Wocjtowicz E, Krivtsov AV, Rombouts E, Armstrong SA, Taskesen E, Haanstra JR, Beverloo HB, Döhner H, Hudson WA, Kersey JH, Delwel R, Kumar AR. Bindels EM, et al. Among authors: kersey jh. Blood. 2012 Jun 14;119(24):5838-49. doi: 10.1182/blood-2011-11-393827. Epub 2012 May 2. Blood. 2012. PMID: 22553314 Free PMC article.

4

Molecular rearrangements of the MLL gene are present in most cases of infant acute myeloid leukemia and are strongly correlated with monocytic or myelomonocytic phenotypes.

Sorensen PH, Chen CS, Smith FO, Arthur DC, Domer PH, Bernstein ID, Korsmeyer SJ, Hammond GD, Kersey JH. Sorensen PH, et al. Among authors: kersey jh. J Clin Invest. 1994 Jan;93(1):429-37. doi: 10.1172/JCI116978. J Clin Invest. 1994. PMID: 8282816 Free PMC article.

5

FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases.

Yao Q, Nishiuchi R, Li Q, Kumar AR, Hudson WA, Kersey JH. Yao Q, et al. Among authors: kersey jh. Clin Cancer Res. 2003 Oct 1;9(12):4483-93. Clin Cancer Res. 2003. PMID: 14555522

6

MLL gene rearrangements in infant leukemia vary with age at diagnosis and selected demographic factors: a Children's Oncology Group (COG) study.

Sam TN, Kersey JH, Linabery AM, Johnson KJ, Heerema NA, Hilden JM, Davies SM, Reaman GH, Ross JA. Sam TN, et al. Among authors: kersey jh. Pediatr Blood Cancer. 2012 Jun;58(6):836-9. doi: 10.1002/pbc.23274. Epub 2011 Jul 28. Pediatr Blood Cancer. 2012. PMID: 21800415 Free PMC article.

7

The chromosome 4q21 gene (AF-4/FEL) is widely expressed in normal tissues and shows breakpoint diversity in t(4;11)(q21;q23) acute leukemia.

Chen CS, Hilden JM, Frestedt J, Domer PH, Moore R, Korsmeyer SJ, Kersey JH. Chen CS, et al. Among authors: kersey jh. Blood. 1993 Aug 15;82(4):1080-5. Blood. 1993. PMID: 8353274 Free article.

8

Molecular rearrangements on chromosome 11q23 predominate in infant acute lymphoblastic leukemia and are associated with specific biologic variables and poor outcome.

Chen CS, Sorensen PH, Domer PH, Reaman GH, Korsmeyer SJ, Heerema NA, Hammond GD, Kersey JH. Chen CS, et al. Among authors: kersey jh. Blood. 1993 May 1;81(9):2386-93. Blood. 1993. PMID: 8481519 Free article.

9

Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.

Korsmeyer SJ, Arnold A, Bakhshi A, Ravetch JV, Siebenlist U, Hieter PA, Sharrow SO, LeBien TW, Kersey JH, Poplack DG, Leder P, Waldmann TA. Korsmeyer SJ, et al. Among authors: kersey jh. J Clin Invest. 1983 Feb;71(2):301-13. doi: 10.1172/jci110770. J Clin Invest. 1983. PMID: 6401769 Free PMC article.

10

A role for MEIS1 in MLL-fusion gene leukemia.

Kumar AR, Li Q, Hudson WA, Chen W, Sam T, Yao Q, Lund EA, Wu B, Kowal BJ, Kersey JH. Kumar AR, et al. Among authors: kersey jh. Blood. 2009 Feb 19;113(8):1756-8. doi: 10.1182/blood-2008-06-163287. Epub 2008 Dec 24. Blood. 2009. PMID: 19109563 Free PMC article.

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