Hazuda DJ - Search Results

1

Integracides: tetracyclic triterpenoid inhibitors of HIV-1 integrase produced by Fusarium sp.

Singh SB, Zink DL, Dombrowski AW, Polishook JD, Ondeyka JG, Hirshfield J, Felock P, Hazuda DJ. Singh SB, et al. Among authors: hazuda dj. Bioorg Med Chem. 2003 Apr 3;11(7):1577-82. doi: 10.1016/s0968-0896(02)00529-1. Bioorg Med Chem. 2003. PMID: 12628681

2

The role of manganese in promoting multimerization and assembly of human immunodeficiency virus type 1 integrase as a catalytically active complex on immobilized long terminal repeat substrates.

Wolfe AL, Felock PJ, Hastings JC, Blau CU, Hazuda DJ. Wolfe AL, et al. Among authors: hazuda dj. J Virol. 1996 Mar;70(3):1424-32. doi: 10.1128/JVI.70.3.1424-1432.1996. J Virol. 1996. PMID: 8627659 Free PMC article.

3

Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.

Hazuda D, Felock P, Hastings J, Pramanik B, Wolfe A, Goodarzi G, Vora A, Brackmann K, Grandgenett D. Hazuda D, et al. J Virol. 1997 Jan;71(1):807-11. doi: 10.1128/JVI.71.1.807-811.1997. J Virol. 1997. PMID: 8985421 Free PMC article.

4

Differential divalent cation requirements uncouple the assembly and catalytic reactions of human immunodeficiency virus type 1 integrase.

Hazuda DJ, Felock PJ, Hastings JC, Pramanik B, Wolfe AL. Hazuda DJ, et al. J Virol. 1997 Sep;71(9):7005-11. doi: 10.1128/JVI.71.9.7005-7011.1997. J Virol. 1997. PMID: 9261430 Free PMC article.

5

Discovery and analysis of inhibitors of the human immunodeficiency integrase.

Hazuda D, Felock PJ, Hastings JC, Pramanik B, Wolfe AL. Hazuda D, et al. Drug Des Discov. 1997 May;15(1):17-24. Drug Des Discov. 1997. PMID: 9332828

6

Isolation and characterization of novel human immunodeficiency virus integrase inhibitors from fungal metabolites.

Hazuda D, Blau CU, Felock P, Hastings J, Pramanik B, Wolfe A, Bushman F, Farnet C, Goetz M, Williams M, Silverman K, Lingham R, Singh S. Hazuda D, et al. Antivir Chem Chemother. 1999 Mar;10(2):63-70. doi: 10.1177/095632029901000202. Antivir Chem Chemother. 1999. PMID: 10335400 Free article.

7

Efficiency and fidelity of full-site integration reactions using recombinant simian immunodeficiency virus integrase.

Goodarzi G, Pursley M, Felock P, Witmer M, Hazuda D, Brackmann K, Grandgenett D. Goodarzi G, et al. J Virol. 1999 Oct;73(10):8104-11. doi: 10.1128/JVI.73.10.8104-8111.1999. J Virol. 1999. PMID: 10482559 Free PMC article.

8

Purification, solution properties and crystallization of SIV integrase containing a continuous core and C-terminal domain.

Li Y, Yan Y, Zugay-Murphy J, Xu B, Cole JL, Witmer M, Felock P, Wolfe A, Hazuda D, Sardana MK, Chen Z, Kuo LC, Sardana VV. Li Y, et al. Acta Crystallogr D Biol Crystallogr. 1999 Nov;55(Pt 11):1906-10. doi: 10.1107/s0907444999009610. Acta Crystallogr D Biol Crystallogr. 1999. PMID: 10531491

9

Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells.

Hazuda DJ, Felock P, Witmer M, Wolfe A, Stillmock K, Grobler JA, Espeseth A, Gabryelski L, Schleif W, Blau C, Miller MD. Hazuda DJ, et al. Science. 2000 Jan 28;287(5453):646-50. doi: 10.1126/science.287.5453.646. Science. 2000. PMID: 10649997

10

X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.

Chen Z, Yan Y, Munshi S, Li Y, Zugay-Murphy J, Xu B, Witmer M, Felock P, Wolfe A, Sardana V, Emini EA, Hazuda D, Kuo LC. Chen Z, et al. J Mol Biol. 2000 Feb 18;296(2):521-33. doi: 10.1006/jmbi.1999.3451. J Mol Biol. 2000. PMID: 10669606

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