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Elderly patients with fluoropyrimidine and thymidylate synthase inhibitor-resistant advanced colorectal cancer derive similar benefit without excessive toxicity when treated with irinotecan monotherapy.
Chau I, Norman AR, Cunningham D, Waters JS, Topham C, Middleton G, Hill M, Ross PJ, Katopodis R, Stewart G, Oates JR. Chau I, et al. Among authors: oates jr. Br J Cancer. 2004 Oct 18;91(8):1453-8. doi: 10.1038/sj.bjc.6602169. Br J Cancer. 2004. PMID: 15365570 Free PMC article. Clinical Trial.
A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer.
Chau I, Norman AR, Cunningham D, Tait D, Ross PJ, Iveson T, Hill M, Hickish T, Lofts F, Jodrell D, Webb A, Oates JR. Chau I, et al. Among authors: oates jr. Ann Oncol. 2005 Apr;16(4):549-57. doi: 10.1093/annonc/mdi116. Epub 2005 Feb 2. Ann Oncol. 2005. PMID: 15695501 Free article. Clinical Trial.
Twelve weeks of protracted venous infusion of fluorouracil (5-FU) is as effective as 6 months of bolus 5-FU and folinic acid as adjuvant treatment in colorectal cancer.
Saini A, Norman AR, Cunningham D, Chau I, Hill M, Tait D, Hickish T, Iveson T, Lofts F, Jodrell D, Ross PJ, Oates J. Saini A, et al. Among authors: oates j. Br J Cancer. 2003 Jun 16;88(12):1859-65. doi: 10.1038/sj.bjc.6600995. Br J Cancer. 2003. PMID: 12799627 Free PMC article. Clinical Trial.
945 results