Martin JR - Search Results

1

Influence of the 5-HT6 receptor on acetylcholine release in the cortex: pharmacological characterization of 4-(2-bromo-6-pyrrolidin-1-ylpyridine-4-sulfonyl)phenylamine, a potent and selective 5-HT6 receptor antagonist.

Riemer C, Borroni E, Levet-Trafit B, Martin JR, Poli S, Porter RH, Bös M. Riemer C, et al. Among authors: martin jr. J Med Chem. 2003 Mar 27;46(7):1273-6. doi: 10.1021/jm021085c. J Med Chem. 2003. PMID: 12646038

2

Novel agonists of 5HT2C receptors. Synthesis and biological evaluation of substituted 2-(indol-1-yl)-1-methylethylamines and 2-(indeno[1,2-b]pyrrol-1-yl)-1-methylethylamines. Improved therapeutics for obsessive compulsive disorder.

Bös M, Jenck F, Martin JR, Moreau JL, Sleight AJ, Wichmann J, Widmer U. Bös M, et al. Among authors: martin jr. J Med Chem. 1997 Aug 15;40(17):2762-9. doi: 10.1021/jm970030l. J Med Chem. 1997. PMID: 9276022

3

5-HT(6) receptor antagonists: lead optimisation and biological evaluation of N-aryl and N-heteroaryl 4-amino-benzene sulfonamides.

Bös M, Sleight AJ, Godel T, Martin JR, Riemer C, Stadler H. Bös M, et al. Among authors: martin jr. Eur J Med Chem. 2001 Feb;36(2):165-78. doi: 10.1016/s0223-5234(00)01209-5. Eur J Med Chem. 2001. PMID: 11311747

4

Discovery of the imidazo[1,5-a][1,2,4]-triazolo[1,5-d][1,4]benzodiazepine scaffold as a novel, potent and selective GABA(A) alpha5 inverse agonist series.

Achermann G, Ballard TM, Blasco F, Broutin PE, Büttelmann B, Fischer H, Graf M, Hernandez MC, Hilty P, Knoflach F, Koblet A, Knust H, Kurt A, Martin JR, Masciadri R, Porter RH, Stadler H, Thomas AW, Trube G, Wichmann J. Achermann G, et al. Among authors: martin jr. Bioorg Med Chem Lett. 2009 Oct 1;19(19):5746-52. doi: 10.1016/j.bmcl.2009.07.153. Epub 2009 Aug 4. Bioorg Med Chem Lett. 2009. PMID: 19726184

5

5-HT2C receptor agonists: pharmacological characteristics and therapeutic potential.

Martin JR, Bös M, Jenck F, Moreau J, Mutel V, Sleight AJ, Wichmann J, Andrews JS, Berendsen HH, Broekkamp CL, Ruigt GS, Köhler C, Delft AM. Martin JR, et al. J Pharmacol Exp Ther. 1998 Aug;286(2):913-24. J Pharmacol Exp Ther. 1998. PMID: 9694950

6

5HT2C receptor agonists exhibit antidepressant-like properties in the anhedonia model of depression in rats.

Moreau JL, Bös M, Jenck F, Martin JR, Mortas P, Wichmann J. Moreau JL, et al. Among authors: martin jr. Eur Neuropsychopharmacol. 1996 Aug;6(3):169-75. doi: 10.1016/0924-977x(96)00015-6. Eur Neuropsychopharmacol. 1996. PMID: 8880075

7

The role of 5-HT2C receptors in affective disorders.

Jenck F, Bös M, Wichmann J, Stadler H, Martin JR, Moreau JL. Jenck F, et al. Among authors: martin jr. Expert Opin Investig Drugs. 1998 Oct;7(10):1587-99. doi: 10.1517/13543784.7.10.1587. Expert Opin Investig Drugs. 1998. PMID: 15991903

8

Lazabemide for the treatment of Alzheimer's disease: rationale and therapeutic perspectives.

Cesura AM, Borroni E, Gottowik J, Kuhn C, Malherbe P, Martin J, Richards JG. Cesura AM, et al. Adv Neurol. 1999;80:521-8. Adv Neurol. 1999. PMID: 10410766 Review. No abstract available.

9

A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: anxiolytic profile in the rat.

Jenck F, Wichmann J, Dautzenberg FM, Moreau JL, Ouagazzal AM, Martin JR, Lundstrom K, Cesura AM, Poli SM, Roever S, Kolczewski S, Adam G, Kilpatrick G. Jenck F, et al. Among authors: martin jr. Proc Natl Acad Sci U S A. 2000 Apr 25;97(9):4938-43. doi: 10.1073/pnas.090514397. Proc Natl Acad Sci U S A. 2000. PMID: 10758169 Free PMC article.

10

Aniracetam reverses memory impairment in rats.

Martin JR, Moreau JL, Jenck F. Martin JR, et al. Pharmacol Res. 1995 Feb;31(2):133-6. doi: 10.1016/1043-6618(95)80059-x. Pharmacol Res. 1995. PMID: 7596957

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