Doughty L - Search Results

1

Single-chain Fv multimers of the anti-neuraminidase antibody NC10: the residue at position 15 in the V(L) domain of the scFv-0 (V(L)-V(H)) molecule is primarily responsible for formation of a tetramer-trimer equilibrium.

Dolezal O, De Gori R, Walter M, Doughty L, Hattarki M, Hudson PJ, Kortt AA. Dolezal O, et al. Among authors: doughty l. Protein Eng. 2003 Jan;16(1):47-56. doi: 10.1093/proeng/gzg006. Protein Eng. 2003. PMID: 12646692

2

Noncovalent scFv multimers of tumor-targeting anti-Lewis(y) hu3S193 humanized antibody.

Power BE, Doughty L, Shapira DR, Burns JE, Bayly AM, Caine JM, Liu Z, Scott AM, Hudson PJ, Kortt AA. Power BE, et al. Among authors: doughty l. Protein Sci. 2003 Apr;12(4):734-47. doi: 10.1110/ps.0228503. Protein Sci. 2003. PMID: 12649432 Free PMC article.

3

A naturally occurring NAR variable domain binds the Kgp protease from Porphyromonas gingivalis.

Nuttall SD, Krishnan UV, Doughty L, Nathanielsz A, Ally N, Pike RN, Hudson PJ, Kortt AA, Irving RA. Nuttall SD, et al. Among authors: doughty l. FEBS Lett. 2002 Apr 10;516(1-3):80-6. doi: 10.1016/s0014-5793(02)02506-1. FEBS Lett. 2002. PMID: 11959108 Free article.

4

Isolation and characterization of an IgNAR variable domain specific for the human mitochondrial translocase receptor Tom70.

Nuttall SD, Krishnan UV, Doughty L, Pearson K, Ryan MT, Hoogenraad NJ, Hattarki M, Carmichael JA, Irving RA, Hudson PJ. Nuttall SD, et al. Among authors: doughty l. Eur J Biochem. 2003 Sep;270(17):3543-54. doi: 10.1046/j.1432-1033.2003.03737.x. Eur J Biochem. 2003. PMID: 12919318 Free article.

5

Selection and affinity maturation of IgNAR variable domains targeting Plasmodium falciparum AMA1.

Nuttall SD, Humberstone KS, Krishnan UV, Carmichael JA, Doughty L, Hattarki M, Coley AM, Casey JL, Anders RF, Foley M, Irving RA, Hudson PJ. Nuttall SD, et al. Among authors: doughty l. Proteins. 2004 Apr 1;55(1):187-97. doi: 10.1002/prot.20005. Proteins. 2004. PMID: 14997552

6

Dimerisation strategies for shark IgNAR single domain antibody fragments.

Simmons DP, Abregu FA, Krishnan UV, Proll DF, Streltsov VA, Doughty L, Hattarki MK, Nuttall SD. Simmons DP, et al. Among authors: doughty l. J Immunol Methods. 2006 Aug 31;315(1-2):171-84. doi: 10.1016/j.jim.2006.07.019. Epub 2006 Aug 28. J Immunol Methods. 2006. PMID: 16962608

7

Structural model for the interaction of a designed Ankyrin Repeat Protein with the human epidermal growth factor receptor 2.

Epa VC, Dolezal O, Doughty L, Xiao X, Jost C, Plückthun A, Adams TE. Epa VC, et al. Among authors: doughty l. PLoS One. 2013;8(3):e59163. doi: 10.1371/journal.pone.0059163. Epub 2013 Mar 19. PLoS One. 2013. PMID: 23527120 Free PMC article.

8

Biodistributions of intact monoclonal antibodies and fragments of BLCA-38, a new prostate cancer directed antibody.

Carter T, Sterling-Levis K, Ow K, Doughty L, Hattarki M, Shapira D, Hewish D, Kortt AA, Russell PJ. Carter T, et al. Among authors: doughty l. Cancer Immunol Immunother. 2004 Jun;53(6):533-42. doi: 10.1007/s00262-003-0460-1. Epub 2004 Jan 13. Cancer Immunol Immunother. 2004. PMID: 14722669 Free PMC article.

9

Cytotoxic properties of immunoconjugates containing melittin-like peptide 101 against prostate cancer: in vitro and in vivo studies.

Russell PJ, Hewish D, Carter T, Sterling-Levis K, Ow K, Hattarki M, Doughty L, Guthrie R, Shapira D, Molloy PL, Werkmeister JA, Kortt AA. Russell PJ, et al. Among authors: doughty l. Cancer Immunol Immunother. 2004 May;53(5):411-21. doi: 10.1007/s00262-003-0457-9. Epub 2004 Jan 13. Cancer Immunol Immunother. 2004. PMID: 14722668 Free PMC article.

10

Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin.

Lawrence SL, Feil SC, Holien JK, Kuiper MJ, Doughty L, Dolezal O, Mulhern TD, Tweten RK, Parker MW. Lawrence SL, et al. Among authors: doughty l. Front Immunol. 2012 Nov 5;3:330. doi: 10.3389/fimmu.2012.00330. eCollection 2012. Front Immunol. 2012. PMID: 23181061 Free PMC article.

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