Parthun MR - Search Results

1

Depsipeptide (FR901228) induces histone acetylation and inhibition of histone deacetylase in chronic lymphocytic leukemia cells concurrent with activation of caspase 8-mediated apoptosis and down-regulation of c-FLIP protein.

Aron JL, Parthun MR, Marcucci G, Kitada S, Mone AP, Davis ME, Shen T, Murphy T, Wickham J, Kanakry C, Lucas DM, Reed JC, Grever MR, Byrd JC. Aron JL, et al. Among authors: parthun mr. Blood. 2003 Jul 15;102(2):652-8. doi: 10.1182/blood-2002-12-3794. Epub 2003 Mar 20. Blood. 2003. PMID: 12649137 Free article.

2

Depsipeptide (FR 901228) promotes histone acetylation, gene transcription, apoptosis and its activity is enhanced by DNA methyltransferase inhibitors in AML1/ETO-positive leukemic cells.

Klisovic MI, Maghraby EA, Parthun MR, Guimond M, Sklenar AR, Whitman SP, Chan KK, Murphy T, Anon J, Archer KJ, Rush LJ, Plass C, Grever MR, Byrd JC, Marcucci G. Klisovic MI, et al. Among authors: parthun mr. Leukemia. 2003 Feb;17(2):350-8. doi: 10.1038/sj.leu.2402776. Leukemia. 2003. PMID: 12592335

3

The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells.

Lucas DM, Davis ME, Parthun MR, Mone AP, Kitada S, Cunningham KD, Flax EL, Wickham J, Reed JC, Byrd JC, Grever MR. Lucas DM, et al. Among authors: parthun mr. Leukemia. 2004 Jul;18(7):1207-14. doi: 10.1038/sj.leu.2403388. Leukemia. 2004. PMID: 15116122

4

A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia.

Byrd JC, Marcucci G, Parthun MR, Xiao JJ, Klisovic RB, Moran M, Lin TS, Liu S, Sklenar AR, Davis ME, Lucas DM, Fischer B, Shank R, Tejaswi SL, Binkley P, Wright J, Chan KK, Grever MR. Byrd JC, et al. Among authors: parthun mr. Blood. 2005 Feb 1;105(3):959-67. doi: 10.1182/blood-2004-05-1693. Epub 2004 Oct 5. Blood. 2005. PMID: 15466934 Free article. Clinical Trial.

5

Histone H4 acetylation dynamics determined by stable isotope labeling with amino acids in cell culture and mass spectrometry.

Su X, Zhang L, Lucas DM, Davis ME, Knapp AR, Green-Church KB, Marcucci G, Parthun MR, Byrd JC, Freitas MA. Su X, et al. Among authors: parthun mr. Anal Biochem. 2007 Apr 1;363(1):22-34. doi: 10.1016/j.ab.2006.12.031. Epub 2006 Dec 20. Anal Biochem. 2007. PMID: 17286952 Free PMC article.

6

Validation of an LC-MS based approach for profiling histones in chronic lymphocytic leukemia.

Su X, Lucas DM, Zhang L, Xu H, Zabrouskov V, Davis ME, Knapp AR, Young DC, Payne PR, Parthun MR, Marcucci G, Grever MR, Byrd JC, Freitas MA. Su X, et al. Among authors: parthun mr. Proteomics. 2009 Mar;9(5):1197-206. doi: 10.1002/pmic.200800333. Proteomics. 2009. PMID: 19253275 Free PMC article.

7

Depsipeptide (FR901228) inhibits proliferation and induces apoptosis in primary and metastatic human uveal melanoma cell lines.

Klisovic DD, Katz SE, Effron D, Klisovic MI, Wickham J, Parthun MR, Guimond M, Marcucci G. Klisovic DD, et al. Among authors: parthun mr. Invest Ophthalmol Vis Sci. 2003 Jun;44(6):2390-8. doi: 10.1167/iovs.02-1052. Invest Ophthalmol Vis Sci. 2003. PMID: 12766035

8

Differential expression of histone post-translational modifications in acute myeloid and chronic lymphocytic leukemia determined by high-pressure liquid chromatography and mass spectrometry.

Zhang L, Freitas MA, Wickham J, Parthun MR, Klisovic MI, Marcucci G, Byrd JC. Zhang L, et al. Among authors: parthun mr. J Am Soc Mass Spectrom. 2004 Jan;15(1):77-86. doi: 10.1016/j.jasms.2003.10.001. J Am Soc Mass Spectrom. 2004. PMID: 14698558 Free article.

9

Histone H4 N-terminal acetylation in Kasumi-1 cells treated with depsipeptide determined by acetic acid-urea polyacrylamide gel electrophoresis, amino acid coded mass tagging, and mass spectrometry.

Zhang L, Su X, Liu S, Knapp AR, Parthun MR, Marcucci G, Freitas MA. Zhang L, et al. Among authors: parthun mr. J Proteome Res. 2007 Jan;6(1):81-8. doi: 10.1021/pr060139u. J Proteome Res. 2007. PMID: 17203951 Free PMC article.

10

Quantitative profiling of histone post-translational modifications by stable isotope labeling.

Knapp AR, Ren C, Su X, Lucas DM, Byrd JC, Freitas MA, Parthun MR. Knapp AR, et al. Among authors: parthun mr. Methods. 2007 Mar;41(3):312-9. doi: 10.1016/j.ymeth.2006.08.017. Methods. 2007. PMID: 17309842 Free PMC article.

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