Ng SC - Search Results

1

Biological activity of A-289099: an orally active tubulin-binding indolyloxazoline derivative.

Tahir SK, Nukkala MA, Zielinski Mozny NA, Credo RB, Warner RB, Li Q, Woods KW, Claiborne A, Gwaltney SL 2nd, Frost DJ, Sham HL, Rosenberg SH, Ng SC. Tahir SK, et al. Among authors: ng sc. Mol Cancer Ther. 2003 Mar;2(3):227-33. Mol Cancer Ther. 2003. PMID: 12657717

2

Synthesis and biological evaluation of 2-indolyloxazolines as a new class of tubulin polymerization inhibitors. Discovery of A-289099 as an orally active antitumor agent.

Li Q, Woods KW, Claiborne A, Gwaltney SL 2nd, Barr KJ, Liu G, Gehrke L, Credo RB, Hui YH, Lee J, Warner RB, Kovar P, Nukkala MA, Zielinski NA, Tahir SK, Fitzgerald M, Kim KH, Marsh K, Frost D, Ng SC, Rosenberg S, Sham HL. Li Q, et al. Among authors: ng sc. Bioorg Med Chem Lett. 2002 Feb 11;12(3):465-9. doi: 10.1016/s0960-894x(01)00759-4. Bioorg Med Chem Lett. 2002. PMID: 11814821

3

Modulation of drug resistance by alpha-tubulin in paclitaxel-resistant human lung cancer cell lines.

Han EK, Gehrke L, Tahir SK, Credo RB, Cherian SP, Sham H, Rosenberg SH, Ng S. Han EK, et al. Eur J Cancer. 2000 Aug;36(12):1565-71. doi: 10.1016/s0959-8049(00)00145-3. Eur J Cancer. 2000. PMID: 10930805

4

Novel sulfonate analogues of combretastatin A-4: potent antimitotic agents.

Gwaltney SL 2nd, Imade HM, Barr KJ, Li Q, Gehrke L, Credo RB, Warner RB, Lee JY, Kovar P, Wang J, Nukkala MA, Zielinski NA, Frost D, Ng SC, Sham HL. Gwaltney SL 2nd, et al. Among authors: ng sc. Bioorg Med Chem Lett. 2001 Apr 9;11(7):871-4. doi: 10.1016/s0960-894x(01)00098-1. Bioorg Med Chem Lett. 2001. PMID: 11294380

5

A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.

Tahir SK, Han EK, Credo B, Jae HS, Pietenpol JA, Scatena CD, Wu-Wong JR, Frost D, Sham H, Rosenberg SH, Ng SC. Tahir SK, et al. Among authors: ng sc. Cancer Res. 2001 Jul 15;61(14):5480-5. Cancer Res. 2001. PMID: 11454695

6

Human Chk1 expression is dispensable for somatic cell death and critical for sustaining G2 DNA damage checkpoint.

Chen Z, Xiao Z, Chen J, Ng SC, Sowin T, Sham H, Rosenberg S, Fesik S, Zhang H. Chen Z, et al. Among authors: ng sc. Mol Cancer Ther. 2003 Jun;2(6):543-8. Mol Cancer Ther. 2003. PMID: 12813133

7

Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.

Tahir SK, Yang X, Anderson MG, Morgan-Lappe SE, Sarthy AV, Chen J, Warner RB, Ng SC, Fesik SW, Elmore SW, Rosenberg SH, Tse C. Tahir SK, et al. Among authors: ng sc. Cancer Res. 2007 Feb 1;67(3):1176-83. doi: 10.1158/0008-5472.CAN-06-2203. Cancer Res. 2007. PMID: 17283153

8

Synergistic effect of paclitaxel and 4-hydroxytamoxifen on estrogen receptor-negative colon cancer and lung cancer cell lines.

Gu WZ, Chen Z, Tahir SK, Rosenberg SH, Ng SC. Gu WZ, et al. Among authors: ng sc. Anticancer Drugs. 1999 Nov;10(10):895-901. doi: 10.1097/00001813-199911000-00005. Anticancer Drugs. 1999. PMID: 10630357

9

Effect of novel CAAX peptidomimetic farnesyltransferase inhibitor on angiogenesis in vitro and in vivo.

Gu WZ, Tahir SK, Wang YC, Zhang HC, Cherian SP, O'Connor S, Leal JA, Rosenberg SH, Ng SC. Gu WZ, et al. Among authors: ng sc. Eur J Cancer. 1999 Sep;35(9):1394-401. doi: 10.1016/s0959-8049(99)00132-x. Eur J Cancer. 1999. PMID: 10658533

10

Modulation of paclitaxel resistance by annexin IV in human cancer cell lines.

Han EK, Tahir SK, Cherian SP, Collins N, Ng SC. Han EK, et al. Among authors: ng sc. Br J Cancer. 2000 Jul;83(1):83-8. doi: 10.1054/bjoc.2000.1311. Br J Cancer. 2000. PMID: 10883672 Free PMC article.

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