Deadman JJ - Search Results

1

Generation of ligand conformations in continuum solvent consistent with protein active site topology: application to thrombin.

Greenidge PA, Mérette SA, Beck R, Dodson G, Goodwin CA, Scully MF, Spencer J, Weiser J, Deadman JJ. Greenidge PA, et al. Among authors: deadman jj. J Med Chem. 2003 Apr 10;46(8):1293-305. doi: 10.1021/jm021028j. J Med Chem. 2003. PMID: 12672230

2

Inhibition of human alpha-thrombin by a phosphonate tripeptide proceeds via a metastable pentacoordinated phosphorus intermediate.

Skordalakes E, Dodson GG, Green DS, Goodwin CA, Scully MF, Hudson HR, Kakkar VV, Deadman JJ. Skordalakes E, et al. Among authors: deadman jj. J Mol Biol. 2001 Aug 17;311(3):549-55. doi: 10.1006/jmbi.2001.4872. J Mol Biol. 2001. PMID: 11493008

3

The use of isosteric bonds in the design of thrombin inhibitors.

Scully MF, Deadman J, Cheng L, Goodwin CA, Ellis V, Kakkar VV, Claeson G. Scully MF, et al. Adv Exp Med Biol. 1993;340:131-41. doi: 10.1007/978-1-4899-2418-6_12. Adv Exp Med Biol. 1993. PMID: 8154330 Review. No abstract available.

4

Substrate-related phosphonopeptides as thrombin inhibitors.

Cheng L, Goodwin CA, Scully MF, Deadman J, Claeson G. Cheng L, et al. Adv Exp Med Biol. 1993;340:179-84. doi: 10.1007/978-1-4899-2418-6_15. Adv Exp Med Biol. 1993. PMID: 8154334 Review. No abstract available.

5

Structure/function aspects of neutral P1 residue peptide inhibitors of thrombin.

Deadman J, Claeson G, Scully MF. Deadman J, et al. J Enzyme Inhib. 1995;9(1):29-41. doi: 10.3109/14756369509040679. J Enzyme Inhib. 1995. PMID: 8568564

6

Characterization of a class of peptide boronates with neutral P1 side chains as highly selective inhibitors of thrombin.

Deadman JJ, Elgendy S, Goodwin CA, Green D, Baban JA, Patel G, Skordalakes E, Chino N, Claeson G, Kakkar VV, et al. Deadman JJ, et al. J Med Chem. 1995 Apr 28;38(9):1511-22. doi: 10.1021/jm00009a012. J Med Chem. 1995. PMID: 7739010

7

Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide.

Skordalakes E, Elgendy S, Goodwin CA, Green D, Scully MF, Kakkar VV, Freyssinet JM, Dodson G, Deadman JJ. Skordalakes E, et al. Among authors: deadman jj. Biochemistry. 1998 Oct 13;37(41):14420-7. doi: 10.1021/bi980225a. Biochemistry. 1998. PMID: 9772168

8

Design of novel types of thrombin inhibitors based on modified D-Phe-Pro-Arg sequences.

Claeson G, Elgendy S, Cheng L, Chino N, Goodwin CA, Scully MF, Deadman J. Claeson G, et al. Adv Exp Med Biol. 1993;340:83-9. doi: 10.1007/978-1-4899-2418-6_8. Adv Exp Med Biol. 1993. PMID: 8154346 No abstract available.

9

Heparin enhances the catalytic activity of des-ETW-thrombin.

Goodwin CA, Deadman JJ, Le Bonniec BF, Elgendy S, Kakkar VV, Scully MF. Goodwin CA, et al. Among authors: deadman jj. Biochem J. 1996 Apr 1;315 ( Pt 1)(Pt 1):77-83. doi: 10.1042/bj3150077. Biochem J. 1996. PMID: 8670135 Free PMC article.

10

Thrombin receptor activating peptide does not stimulate platelet procoagulant activity.

Goodwin CA, Wheeler-Jones CP, Kakkar VV, Deadman JJ, Authi KS, Scully MF. Goodwin CA, et al. Among authors: deadman jj. Biochem Biophys Res Commun. 1994 Jul 15;202(1):321-7. doi: 10.1006/bbrc.1994.1930. Biochem Biophys Res Commun. 1994. PMID: 8037727

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

40 results

Search Page

Filters