Patterson SE - Search Results

1

Inhibitors of the IMPDH enzyme as potential anti-bovine viral diarrhoea virus agents.

Stuyver LJ, Lostia S, Patterson SE, Clark JL, Watanabe KA, Otto MJ, Pankiewicz KW. Stuyver LJ, et al. Among authors: patterson se. Antivir Chem Chemother. 2002 Nov;13(6):345-52. doi: 10.1177/095632020201300602. Antivir Chem Chemother. 2002. PMID: 12718406 Free article.

2

Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia.

Pankiewicz KW, Lesiak-Watanabe KB, Watanabe KA, Patterson SE, Jayaram HN, Yalowitz JA, Miller MD, Seidman M, Majumdar A, Prehna G, Goldstein BM. Pankiewicz KW, et al. Among authors: patterson se. J Med Chem. 2002 Jan 31;45(3):703-12. doi: 10.1021/jm0104116. J Med Chem. 2002. PMID: 11806722

3

Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target.

Pankiewicz KW, Patterson SE, Black PL, Jayaram HN, Risal D, Goldstein BM, Stuyver LJ, Schinazi RF. Pankiewicz KW, et al. Among authors: patterson se. Curr Med Chem. 2004 Apr;11(7):887-900. doi: 10.2174/0929867043455648. Curr Med Chem. 2004. PMID: 15083807 Review.

4

Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.

Clark JL, Hollecker L, Mason JC, Stuyver LJ, Tharnish PM, Lostia S, McBrayer TR, Schinazi RF, Watanabe KA, Otto MJ, Furman PA, Stec WJ, Patterson SE, Pankiewicz KW. Clark JL, et al. Among authors: patterson se. J Med Chem. 2005 Aug 25;48(17):5504-8. doi: 10.1021/jm0502788. J Med Chem. 2005. PMID: 16107149

5

Synthesis and in vitro anti-HCV activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides.

Shi J, Du J, Ma T, Pankiewicz KW, Patterson SE, Hassan AE, Tharnish PM, McBrayer TR, Lostia S, Stuyver LJ, Watanabe KA, Chu CK, Schinazi RF, Otto MJ. Shi J, et al. Among authors: patterson se. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):875-9. doi: 10.1081/ncn-200059224. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16248053

6

Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one and its 3'-deoxysugar analogue as potential anti-hepatitis C virus agents.

Wang P, Hollecker L, Pankiewicz KW, Patterson SE, Whitaker T, McBrayer TR, Tharnish PM, Stuyver LJ, Schinazi RF, Otto MJ, Watanabe KA. Wang P, et al. Among authors: patterson se. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):957-60. doi: 10.1081/ncn-200059314. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16248071

7

Synthesis of 5'-C-methyl-1',3'-dioxolan-4'-yl nucleosides.

Du J, Patterson S, Shi J, Chun BK, Stuyver LJ, Watanabe KA. Du J, et al. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1243-5. doi: 10.1016/j.bmcl.2003.12.060. Bioorg Med Chem Lett. 2004. PMID: 14980674

8

Synthesis of N3,5'-cyclo-4-(beta-D-ribofuranosyl)-vic-triazolo[4,5-b]pyridin-5-one, a novel compound with anti-hepatitis C virus activity.

Wang P, Hollecker L, Pankiewicz KW, Patterson SE, Whitaker T, McBrayer TR, Tharnish PM, Sidwell RW, Stuyver LJ, Otto MJ, Schinazi RF, Watanabe KA. Wang P, et al. Among authors: patterson se. J Med Chem. 2004 Nov 18;47(24):6100-3. doi: 10.1021/jm0401210. J Med Chem. 2004. PMID: 15537363

9

Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system.

Shi J, Du J, Ma T, Pankiewicz KW, Patterson SE, Tharnish PM, McBrayer TR, Stuyver LJ, Otto MJ, Chu CK, Schinazi RF, Watanabe KA. Shi J, et al. Among authors: patterson se. Bioorg Med Chem. 2005 Mar 1;13(5):1641-52. doi: 10.1016/j.bmc.2004.12.011. Bioorg Med Chem. 2005. PMID: 15698782

10

Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase.

Rejman D, Olesiak M, Chen L, Patterson SE, Wilson D, Jayaram HN, Hedstrom L, Pankiewicz KW. Rejman D, et al. Among authors: patterson se. J Med Chem. 2006 Aug 10;49(16):5018-22. doi: 10.1021/jm060479r. J Med Chem. 2006. PMID: 16884314

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