Nicolaou KC - Search Results

1

A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR.

Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer JL, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JG, Noel JP, Nicolaou KC, Evans RM. Downes M, et al. Among authors: nicolaou kc. Mol Cell. 2003 Apr;11(4):1079-92. doi: 10.1016/s1097-2765(03)00104-7. Mol Cell. 2003. PMID: 12718892 Free PMC article.

2

Discovery and optimization of non-steroidal FXR agonists from natural product-like libraries.

Nicolaou KC, Evans RM, Roecker AJ, Hughes R, Downes M, Pfefferkorn JA. Nicolaou KC, et al. Org Biomol Chem. 2003 Mar 21;1(6):908-20. Org Biomol Chem. 2003. PMID: 12929628

3

Novel strategies for the solid phase synthesis of substituted indolines and indoles.

Nicolaou KC, Roecker AJ, Hughes R, van Summeren R, Pfefferkorn JA, Winssinger N. Nicolaou KC, et al. Bioorg Med Chem. 2003 Feb 6;11(3):465-76. doi: 10.1016/s0968-0896(02)00386-3. Bioorg Med Chem. 2003. PMID: 12517442

4

Studies towards the synthesis of azadirachtin: enantioselective entry into the azadirachtin framework through cascade reactions.

Nicolaou KC, Roecker AJ, Monenschein H, Guntupalli P, Follmann M. Nicolaou KC, et al. Angew Chem Int Ed Engl. 2003 Aug 11;42(31):3637-42. doi: 10.1002/anie.200351744. Angew Chem Int Ed Engl. 2003. PMID: 12916035 No abstract available.

5

Combinatorial synthesis through disulfide exchange: discovery of potent psammaplin A type antibacterial agents active against methicillin-resistant Staphylococcus aureus (MRSA).

Nicolaou KC, Hughes R, Pfefferkorn JA, Barluenga S, Roecker AJ. Nicolaou KC, et al. Chemistry. 2001 Oct 1;7(19):4280-95. doi: 10.1002/1521-3765(20011001)7:19<4280::aid-chem4280>3.0.co;2-3. Chemistry. 2001. PMID: 11686609

6

Model studies towards azadirachtin: part 2. Construction of the crowded C8-C14 bond by transition metal chemistry.

Nicolaou KC, Roecker AJ, Follmann M, Baati R. Nicolaou KC, et al. Angew Chem Int Ed Engl. 2002 Jun 17;41(12):2107-10. Angew Chem Int Ed Engl. 2002. PMID: 19746611 No abstract available.

7

Studies toward the synthesis of azadirachtin, part 1: total synthesis of a fully functionalized ABC ring framework and coupling with a norbornene domain.

Nicolaou KC, Sasmal PK, Roecker AJ, Sun XW, Mandal S, Converso A. Nicolaou KC, et al. Angew Chem Int Ed Engl. 2005 May 30;44(22):3443-7. doi: 10.1002/anie.200500216. Angew Chem Int Ed Engl. 2005. PMID: 15846829 No abstract available.

8

Model studies towards azadirachtin: part 1. Construction of the crowded C8-C14 bond by radical chemistry.

Nicolaou KC, Follmann M, Roecker AJ, Hunt KW. Nicolaou KC, et al. Angew Chem Int Ed Engl. 2002 Jun 17;41(12):2103-6. Angew Chem Int Ed Engl. 2002. PMID: 19746610 No abstract available.

9

Discovery of novel antibacterial agents active against methicillin-resistant Staphylococcus aureus from combinatorial benzopyran libraries.

Nicolaou KC, Roecker AJ, Barluenga S, Pfefferkorn JA, Cao GQ. Nicolaou KC, et al. Chembiochem. 2001 Jun 1;2(6):460-5. doi: 10.1002/1439-7633(20010601)2:6<460::AID-CBIC460>3.0.CO;2-2. Chembiochem. 2001. PMID: 11828478 No abstract available.

10

Studies toward the synthesis of azadirachtin, part 2: construction of fully functionalized ABCD ring frameworks and unusual intramolecular reactions induced by close-proximity effects.

Nicolaou KC, Sasmal PK, Koftis TV, Converso A, Loizidou E, Kaiser F, Roecker AJ, Dellios CC, Sun XW, Petrovic G. Nicolaou KC, et al. Angew Chem Int Ed Engl. 2005 May 30;44(22):3447-52. doi: 10.1002/anie.200500217. Angew Chem Int Ed Engl. 2005. PMID: 15849805 No abstract available.

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