Thompson KL - Search Results

1

Selection of drugs to test the specificity of the Tg.AC assay by screening for induction of the gadd153 promoter in vitro.

Thompson KL, Sistare FD. Thompson KL, et al. Toxicol Sci. 2003 Aug;74(2):260-70. doi: 10.1093/toxsci/kfg113. Epub 2003 May 2. Toxicol Sci. 2003. PMID: 12730611

2

Evaluation of the Tg.AC transgenic mouse assay for testing the human carcinogenic potential of pharmaceuticals--practical pointers, mechanistic clues, and new questions.

Sistare FD, Thompson KL, Honchel R, DeGeorge J. Sistare FD, et al. Among authors: thompson kl. Int J Toxicol. 2002 Jan-Feb;21(1):65-79. doi: 10.1080/10915810252826028. Int J Toxicol. 2002. PMID: 11936901 Review.

3

Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components.

Thompson KL, Rosenzweig BA, Weaver JL, Zhang J, Lin KK, Sistare FD. Thompson KL, et al. Toxicol Sci. 2003 Aug;74(2):271-8. doi: 10.1093/toxsci/kfg141. Epub 2003 May 28. Toxicol Sci. 2003. PMID: 12773758

4

An evaluation of the hemizygous transgenic Tg.AC mouse for carcinogenicity testing of pharmaceuticals. I. Evidence for a confounding nonresponder phenotype.

Weaver JL, Contrera JF, Rosenzweig BA, Thompson KL, Faustino PJ, Strong JM, Ellison CD, Anderson LW, Prasanna HR, Long-Bradley PE, Lin KK, Zhang J, Sistare FD. Weaver JL, et al. Among authors: thompson kl. Toxicol Pathol. 1998 Jul-Aug;26(4):532-40. doi: 10.1177/019262339802600409. Toxicol Pathol. 1998. PMID: 9715512

5

An evaluation of the hemizygous transgenic Tg.AC mouse for carcinogenicity testing of pharmaceuticals. II. A genotypic marker that predicts tumorigenic responsiveness.

Thompson KL, Rosenzweig BA, Sistare FD. Thompson KL, et al. Toxicol Pathol. 1998 Jul-Aug;26(4):548-55. doi: 10.1177/019262339802600411. Toxicol Pathol. 1998. PMID: 9715514

6

Evaluation of in vitro reporter gene induction assays for use in a rapid prescreen for compound selection to test specificity in the Tg.AC mouse short-term carcinogenicity assay.

Thompson KL, Rosenzweig BA, Tsong Y, Sistare FD. Thompson KL, et al. Toxicol Sci. 2000 Sep;57(1):43-53. doi: 10.1093/toxsci/57.1.43. Toxicol Sci. 2000. PMID: 10966510

7

Loss of palindromic symmetry in Tg.AC mice with a nonresponder phenotype.

Honchel R, Rosenzweig BA, Thompson KL, Blanchard KT, Furst SM, Stoll RE, Sistare FD. Honchel R, et al. Among authors: thompson kl. Mol Carcinog. 2001 Feb;30(2):99-110. Mol Carcinog. 2001. PMID: 11241757

8

Loss of critical palindromic transgene promoter sequence in chemically induced Tg.AC mouse skin papillomas expressing transgene-derived mRNA.

Thompson KL, Rosenzweig BA, Honchel R, Cannon RE, Blanchard KT, Stoll RE, Sistare FD. Thompson KL, et al. Mol Carcinog. 2001 Dec;32(4):176-86. doi: 10.1002/mc.10009. Mol Carcinog. 2001. PMID: 11746829

9

Identification of platform-independent gene expression markers of cisplatin nephrotoxicity.

Thompson KL, Afshari CA, Amin RP, Bertram TA, Car B, Cunningham M, Kind C, Kramer JA, Lawton M, Mirsky M, Naciff JM, Oreffo V, Pine PS, Sistare FD. Thompson KL, et al. Environ Health Perspect. 2004 Mar;112(4):488-94. doi: 10.1289/ehp.6676. Environ Health Perspect. 2004. PMID: 15033599 Free PMC article.

10

Early alterations in heart gene expression profiles associated with doxorubicin cardiotoxicity in rats.

Thompson KL, Rosenzweig BA, Zhang J, Knapton AD, Honchel R, Lipshultz SE, Retief J, Sistare FD, Herman EH. Thompson KL, et al. Cancer Chemother Pharmacol. 2010 Jul;66(2):303-14. doi: 10.1007/s00280-009-1164-9. Epub 2009 Nov 14. Cancer Chemother Pharmacol. 2010. PMID: 19915844

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