Isacchi A - Search Results

1

A new approach to phosphoserine and phosphothreonine analysis in peptides and proteins: chemical modification, enrichment via solid-phase reversible binding, and analysis by mass spectrometry.

Thaler F, Valsasina B, Baldi R, Xie J, Stewart A, Isacchi A, Kalisz HM, Rusconi L. Thaler F, et al. Among authors: isacchi a. Anal Bioanal Chem. 2003 Jun;376(3):366-73. doi: 10.1007/s00216-003-1919-9. Epub 2003 May 7. Anal Bioanal Chem. 2003. PMID: 12734628

2

Role of the Src homology 2 domains and interdomain regions in ZAP-70 phosphorylation and enzymatic activity.

Magistrelli G, Bosotti R, Valsasina B, Visco C, Perego R, Toma S, Acuto O, Isacchi A. Magistrelli G, et al. Among authors: isacchi a. Eur J Biochem. 1999 Dec;266(3):1166-73. doi: 10.1046/j.1432-1327.1999.00973.x. Eur J Biochem. 1999. PMID: 10583414 Free article.

3

Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding.

Visco C, Magistrelli G, Bosotti R, Perego R, Rusconi L, Toma S, Zamai M, Acuto O, Isacchi A. Visco C, et al. Among authors: isacchi a. Biochemistry. 2000 Mar 14;39(10):2784-91. doi: 10.1021/bi991840x. Biochemistry. 2000. PMID: 10704231

4

Inhibitor affinity chromatography: profiling the specific reactivity of the proteome with immobilized molecules.

Lolli G, Thaler F, Valsasina B, Roletto F, Knapp S, Uggeri M, Bachi A, Matafora V, Storici P, Stewart A, Kalisz HM, Isacchi A. Lolli G, et al. Among authors: isacchi a. Proteomics. 2003 Jul;3(7):1287-98. doi: 10.1002/pmic.200300431. Proteomics. 2003. PMID: 12872229

5

Kinase selectivity profiling by inhibitor affinity chromatography.

Valsasina B, Kalisz HM, Isacchi A. Valsasina B, et al. Among authors: isacchi a. Expert Rev Proteomics. 2004 Oct;1(3):303-15. doi: 10.1586/14789450.1.3.303. Expert Rev Proteomics. 2004. PMID: 15966827 Review.

6

Searching for biomarkers of Aurora-A kinase activity: identification of in vitro substrates through a modified KESTREL approach.

Troiani S, Uggeri M, Moll J, Isacchi A, Kalisz HM, Rusconi L, Valsasina B. Troiani S, et al. Among authors: isacchi a. J Proteome Res. 2005 Jul-Aug;4(4):1296-303. doi: 10.1021/pr050018e. J Proteome Res. 2005. PMID: 16083279

7

Regulation of the wild-type and Y1235D mutant Met kinase activation.

Cristiani C, Rusconi L, Perego R, Schiering N, Kalisz HM, Knapp S, Isacchi A. Cristiani C, et al. Among authors: isacchi a. Biochemistry. 2005 Nov 1;44(43):14110-9. doi: 10.1021/bi051242k. Biochemistry. 2005. PMID: 16245927

8

Crystal structure of the T315I Abl mutant in complex with the aurora kinases inhibitor PHA-739358.

Modugno M, Casale E, Soncini C, Rosettani P, Colombo R, Lupi R, Rusconi L, Fancelli D, Carpinelli P, Cameron AD, Isacchi A, Moll J. Modugno M, et al. Among authors: isacchi a. Cancer Res. 2007 Sep 1;67(17):7987-90. doi: 10.1158/0008-5472.CAN-07-1825. Cancer Res. 2007. PMID: 17804707

9

Cdc7 kinase inhibitors: pyrrolopyridinones as potential antitumor agents. 1. Synthesis and structure-activity relationships.

Vanotti E, Amici R, Bargiotti A, Berthelsen J, Bosotti R, Ciavolella A, Cirla A, Cristiani C, D'Alessio R, Forte B, Isacchi A, Martina K, Menichincheri M, Molinari A, Montagnoli A, Orsini P, Pillan A, Roletto F, Scolaro A, Tibolla M, Valsasina B, Varasi M, Volpi D, Santocanale C. Vanotti E, et al. Among authors: isacchi a. J Med Chem. 2008 Feb 14;51(3):487-501. doi: 10.1021/jm700956r. Epub 2008 Jan 18. J Med Chem. 2008. PMID: 18201066

10

A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity.

Montagnoli A, Valsasina B, Croci V, Menichincheri M, Rainoldi S, Marchesi V, Tibolla M, Tenca P, Brotherton D, Albanese C, Patton V, Alzani R, Ciavolella A, Sola F, Molinari A, Volpi D, Avanzi N, Fiorentini F, Cattoni M, Healy S, Ballinari D, Pesenti E, Isacchi A, Moll J, Bensimon A, Vanotti E, Santocanale C. Montagnoli A, et al. Among authors: isacchi a. Nat Chem Biol. 2008 Jun;4(6):357-65. doi: 10.1038/nchembio.90. Epub 2008 May 11. Nat Chem Biol. 2008. PMID: 18469809

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