Hartman PG - Search Results

1

Novel dihydrofolate reductase inhibitors. Structure-based versus diversity-based library design and high-throughput synthesis and screening.

Wyss PC, Gerber P, Hartman PG, Hubschwerlen C, Locher H, Marty HP, Stahl M. Wyss PC, et al. Among authors: hartman pg. J Med Chem. 2003 Jun 5;46(12):2304-12. doi: 10.1021/jm020495y. J Med Chem. 2003. PMID: 12773035

2

A single amino acid substitution in Staphylococcus aureus dihydrofolate reductase determines trimethoprim resistance.

Dale GE, Broger C, D'Arcy A, Hartman PG, DeHoogt R, Jolidon S, Kompis I, Labhardt AM, Langen H, Locher H, Page MG, Stüber D, Then RL, Wipf B, Oefner C. Dale GE, et al. Among authors: hartman pg. J Mol Biol. 1997 Feb 14;266(1):23-30. doi: 10.1006/jmbi.1996.0770. J Mol Biol. 1997. PMID: 9054967

3

Antibacterial activities of epiroprim, a new dihydrofolate reductase inhibitor, alone and in combination with dapsone.

Locher HH, Schlunegger H, Hartman PG, Angehrn P, Then RL. Locher HH, et al. Among authors: hartman pg. Antimicrob Agents Chemother. 1996 Jun;40(6):1376-81. doi: 10.1128/AAC.40.6.1376. Antimicrob Agents Chemother. 1996. PMID: 8726004 Free PMC article.

4

Molecular aspects and mechanism of action of dihydrofolate reductase inhibitors.

Hartman PG. Hartman PG. J Chemother. 1993 Dec;5(6):369-76. J Chemother. 1993. PMID: 8195828 Review.

5

Discovery of novel and orally active FXR agonists for the potential treatment of dyslipidemia & diabetes.

Richter HG, Benson GM, Blum D, Chaput E, Feng S, Gardes C, Grether U, Hartman P, Kuhn B, Martin RE, Plancher JM, Rudolph MG, Schuler F, Taylor S, Bleicher KH. Richter HG, et al. Bioorg Med Chem Lett. 2011 Jan 1;21(1):191-4. doi: 10.1016/j.bmcl.2010.11.039. Epub 2010 Nov 12. Bioorg Med Chem Lett. 2011. PMID: 21134747

6

Synthesis and evaluation of anilinohexafluoroisopropanols as activators/modulators of LXRalpha and beta.

Panday N, Benz J, Blum-Kaelin D, Bourgeaux V, Dehmlow H, Hartman P, Kuhn B, Ratni H, Warot X, Wright MB. Panday N, et al. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5231-7. doi: 10.1016/j.bmcl.2006.06.081. Epub 2006 Jul 31. Bioorg Med Chem Lett. 2006. PMID: 16876993

7

N-terminal amino acid sequence of the chromosomal dihydrofolate reductase purified from trimethoprim-resistant Staphylococcus aureus.

Hartman PG, Stähli M, Kocher HP, Then RL. Hartman PG, et al. FEBS Lett. 1988 Dec 19;242(1):157-60. doi: 10.1016/0014-5793(88)81006-8. FEBS Lett. 1988. PMID: 3060373 Free article.

8

Characterization of the gene for the chromosomal dihydrofolate reductase (DHFR) of Staphylococcus epidermidis ATCC 14990: the origin of the trimethoprim-resistant S1 DHFR from Staphylococcus aureus?

Dale GE, Broger C, Hartman PG, Langen H, Page MG, Then RL, Stüber D. Dale GE, et al. Among authors: hartman pg. J Bacteriol. 1995 Jun;177(11):2965-70. doi: 10.1128/jb.177.11.2965-2970.1995. J Bacteriol. 1995. PMID: 7768789 Free PMC article.

9

Selective inhibition of dihydrofolate reductase from problem human pathogens.

Then RL, Hartman PG, Kompis I, Santi D. Then RL, et al. Among authors: hartman pg. Adv Exp Med Biol. 1993;338:533-6. doi: 10.1007/978-1-4615-2960-6_108. Adv Exp Med Biol. 1993. PMID: 8304174 No abstract available.

10

Optimization of a novel class of benzimidazole-based farnesoid X receptor (FXR) agonists to improve physicochemical and ADME properties.

Richter HG, Benson GM, Bleicher KH, Blum D, Chaput E, Clemann N, Feng S, Gardes C, Grether U, Hartman P, Kuhn B, Martin RE, Plancher JM, Rudolph MG, Schuler F, Taylor S. Richter HG, et al. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1134-40. doi: 10.1016/j.bmcl.2010.12.123. Epub 2010 Dec 31. Bioorg Med Chem Lett. 2011. PMID: 21269824

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

29 results

Search Page

Filters