Rokosh DG - Search Results

1

The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse.

O'Connell TD, Ishizaka S, Nakamura A, Swigart PM, Rodrigo MC, Simpson GL, Cotecchia S, Rokosh DG, Grossman W, Foster E, Simpson PC. O'Connell TD, et al. Among authors: rokosh dg. J Clin Invest. 2003 Jun;111(11):1783-91. doi: 10.1172/JCI16100. J Clin Invest. 2003. PMID: 12782680 Free PMC article.

2

Knockout of the alpha 1A/C-adrenergic receptor subtype: the alpha 1A/C is expressed in resistance arteries and is required to maintain arterial blood pressure.

Rokosh DG, Simpson PC. Rokosh DG, et al. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9474-9. doi: 10.1073/pnas.132552699. Epub 2002 Jul 1. Proc Natl Acad Sci U S A. 2002. PMID: 12093905 Free PMC article.

3

Alpha(1)-adrenoceptor subtypes mediate negative inotropy in myocardium from alpha(1A/C)-knockout and wild type mice.

McCloskey DT, Rokosh DG, O'Connell TD, Keung EC, Simpson PC, Baker AJ. McCloskey DT, et al. Among authors: rokosh dg. J Mol Cell Cardiol. 2002 Aug;34(8):1007-17. doi: 10.1006/jmcc.2002.2049. J Mol Cell Cardiol. 2002. PMID: 12234770

4

Autonomous and growth factor-induced hypertrophy in cultured neonatal mouse cardiac myocytes. Comparison with rat.

Deng XF, Rokosh DG, Simpson PC. Deng XF, et al. Among authors: rokosh dg. Circ Res. 2000 Oct 27;87(9):781-8. doi: 10.1161/01.res.87.9.781. Circ Res. 2000. PMID: 11055982

5

Cloning and characterization of the mouse alpha1C/A-adrenergic receptor gene and analysis of an alpha1C promoter in cardiac myocytes: role of an MCAT element that binds transcriptional enhancer factor-1 (TEF-1).

O'Connell TD, Rokosh DG, Simpson PC. O'Connell TD, et al. Among authors: rokosh dg. Mol Pharmacol. 2001 May;59(5):1225-34. doi: 10.1124/mol.59.5.1225. Mol Pharmacol. 2001. PMID: 11306707

6

Cloning of the rat alpha 1C-adrenergic receptor from cardiac myocytes. alpha 1C, alpha 1B, and alpha 1D mRNAs are present in cardiac myocytes but not in cardiac fibroblasts.

Stewart AF, Rokosh DG, Bailey BA, Karns LR, Chang KC, Long CS, Kariya K, Simpson PC. Stewart AF, et al. Among authors: rokosh dg. Circ Res. 1994 Oct;75(4):796-802. doi: 10.1161/01.res.75.4.796. Circ Res. 1994. PMID: 7923624

7

Distribution of alpha 1C-adrenergic receptor mRNA in adult rat tissues by RNase protection assay and comparison with alpha 1B and alpha 1D.

Rokosh DG, Bailey BA, Stewart AF, Karns LR, Long CS, Simpson PC. Rokosh DG, et al. Biochem Biophys Res Commun. 1994 May 16;200(3):1177-84. doi: 10.1006/bbrc.1994.1575. Biochem Biophys Res Commun. 1994. PMID: 8185565

8

Alpha1-adrenergic receptor subtype mRNAs are differentially regulated by alpha1-adrenergic and other hypertrophic stimuli in cardiac myocytes in culture and in vivo. Repression of alpha1B and alpha1D but induction of alpha1C.

Rokosh DG, Stewart AF, Chang KC, Bailey BA, Karliner JS, Camacho SA, Long CS, Simpson PC. Rokosh DG, et al. J Biol Chem. 1996 Mar 8;271(10):5839-43. doi: 10.1074/jbc.271.10.5839. J Biol Chem. 1996. PMID: 8621454 Free article.

9

LV systolic performance improves with development of hypertrophy after transverse aortic constriction in mice.

Nakamura A, Rokosh DG, Paccanaro M, Yee RR, Simpson PC, Grossman W, Foster E. Nakamura A, et al. Among authors: rokosh dg. Am J Physiol Heart Circ Physiol. 2001 Sep;281(3):H1104-12. doi: 10.1152/ajpheart.2001.281.3.H1104. Am J Physiol Heart Circ Physiol. 2001. PMID: 11514276 Free article.

10

Chronic hypoxia differentially regulates alpha 1-adrenergic receptor subtype mRNAs and inhibits alpha 1-adrenergic receptor-stimulated cardiac hypertrophy and signaling.

Li HT, Long CS, Rokosh DG, Honbo NY, Karliner JS. Li HT, et al. Among authors: rokosh dg. Circulation. 1995 Aug 15;92(4):918-25. doi: 10.1161/01.cir.92.4.918. Circulation. 1995. PMID: 7641375

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