Le Breton GC - Search Results

1

Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases.

Li Z, Zhang G, Le Breton GC, Gao X, Malik AB, Du X. Li Z, et al. Among authors: le breton gc. J Biol Chem. 2003 Aug 15;278(33):30725-31. doi: 10.1074/jbc.M301838200. Epub 2003 Jun 9. J Biol Chem. 2003. PMID: 12796499 Free article.

2

Identification of Galpha13 as one of the G-proteins that couple to human platelet thromboxane A2 receptors.

Djellas Y, Manganello JM, Antonakis K, Le Breton GC. Djellas Y, et al. Among authors: le breton gc. J Biol Chem. 1999 May 14;274(20):14325-30. doi: 10.1074/jbc.274.20.14325. J Biol Chem. 1999. PMID: 10318854 Free article.

3

Enrichment of platelet phospholipids with eicosapentaenoic acid and docosahexaenoic acid inhibits thromboxane A2/prostaglandin H2 receptor binding and function.

Swann PG, Parent CA, Croset M, Fonlupt P, Lagarde M, Venton DL, Le Breton GC. Swann PG, et al. Among authors: le breton gc. J Biol Chem. 1990 Dec 15;265(35):21692-7. J Biol Chem. 1990. PMID: 2147687 Free article.

4

Identification of Gq as one of the G-proteins which copurify with human platelet thromboxane A2/prostaglandin H2 receptors.

Knezevic I, Borg C, Le Breton GC. Knezevic I, et al. Among authors: le breton gc. J Biol Chem. 1993 Dec 5;268(34):26011-7. J Biol Chem. 1993. PMID: 8245033 Free article.

5

Cyclic AMP-dependent phosphorylation of thromboxane A(2) receptor-associated Galpha(13).

Manganello JM, Djellas Y, Borg C, Antonakis K, Le Breton GC. Manganello JM, et al. Among authors: le breton gc. J Biol Chem. 1999 Sep 24;274(39):28003-10. doi: 10.1074/jbc.274.39.28003. J Biol Chem. 1999. PMID: 10488151 Free article.

6

Signaling through G(alpha)13 switch region I is essential for protease-activated receptor 1-mediated human platelet shape change, aggregation, and secretion.

Huang JS, Dong L, Kozasa T, Le Breton GC. Huang JS, et al. Among authors: le breton gc. J Biol Chem. 2007 Apr 6;282(14):10210-22. doi: 10.1074/jbc.M605678200. Epub 2007 Feb 13. J Biol Chem. 2007. PMID: 17298951 Free article.

7

Mapping of a ligand-binding site for the human thromboxane A2 receptor protein.

Turek JW, Halmos T, Sullivan NL, Antonakis K, Le Breton GC. Turek JW, et al. Among authors: le breton gc. J Biol Chem. 2002 May 10;277(19):16791-7. doi: 10.1074/jbc.M105872200. Epub 2002 Mar 4. J Biol Chem. 2002. PMID: 11877412 Free article.

8

Selective modulation of the human platelet thromboxane A2/prostaglandin H2 receptor by eicosapentaenoic and docosahexaenoic acids in intact platelets and solubilized platelet membranes.

Parent CA, Lagarde M, Venton DL, Le Breton GC. Parent CA, et al. Among authors: le breton gc. J Biol Chem. 1992 Apr 5;267(10):6541-7. J Biol Chem. 1992. PMID: 1532390 Free article.

9

Differential mapping of the amino acids mediating agonist and antagonist coordination with the human thromboxane A2 receptor protein.

Khasawneh FT, Huang JS, Turek JW, Le Breton GC. Khasawneh FT, et al. Among authors: le breton gc. J Biol Chem. 2006 Sep 15;281(37):26951-65. doi: 10.1074/jbc.M507469200. Epub 2006 Jul 12. J Biol Chem. 2006. PMID: 16837469 Free article.

10

The P2Y12 antagonists, 2-methylthioadenosine 5'-monophosphate triethylammonium salt and cangrelor (ARC69931MX), can inhibit human platelet aggregation through a Gi-independent increase in cAMP levels.

Srinivasan S, Mir F, Huang JS, Khasawneh FT, Lam SC, Le Breton GC. Srinivasan S, et al. Among authors: le breton gc. J Biol Chem. 2009 Jun 12;284(24):16108-16117. doi: 10.1074/jbc.M809780200. Epub 2009 Apr 3. J Biol Chem. 2009. PMID: 19346255 Free PMC article.

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