Xu JZ - Search Results

1

Benzoxazinones as PPARgamma agonists. part 1: SAR of three aromatic regions.

Rybczynski PJ, Zeck RE, Combs DW, Turchi I, Burris TP, Xu JZ, Yang M, Demarest KT. Rybczynski PJ, et al. Among authors: xu jz. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2359-62. doi: 10.1016/s0960-894x(03)00401-3. Bioorg Med Chem Lett. 2003. PMID: 12824034

2

Discovery of para-alkylthiophenoxyacetic acids as a novel series of potent and selective PPARdelta agonists.

Zhang R, Wang A, DeAngelis A, Pelton P, Xu J, Zhu P, Zhou L, Demarest K, Murray WV, Kuo GH. Zhang R, et al. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3855-9. doi: 10.1016/j.bmcl.2007.05.007. Epub 2007 May 10. Bioorg Med Chem Lett. 2007. PMID: 17524639

3

Discovery and SAR of para-alkylthiophenoxyacetic acids as potent and selective PPARdelta agonists.

Zhang R, Deangelis A, Wang A, Sieber-McMaster E, Li X, Russell R, Pelton P, Xu J, Zhu P, Zhou L, Demarest K, Murray WV, Kuo GH. Zhang R, et al. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1101-4. doi: 10.1016/j.bmcl.2008.12.113. Epub 2009 Jan 8. Bioorg Med Chem Lett. 2009. PMID: 19168353

4

Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3beta (GSK-3beta) inhibitors.

O'Neill DJ, Shen L, Prouty C, Conway BR, Westover L, Xu JZ, Zhang HC, Maryanoff BE, Murray WV, Demarest KT, Kuo GH. O'Neill DJ, et al. Among authors: xu jz. Bioorg Med Chem. 2004 Jun 15;12(12):3167-85. doi: 10.1016/j.bmc.2004.04.010. Bioorg Med Chem. 2004. PMID: 15158785

5

Synthesis and biological evaluation of 3-aryl-3-(4-phenoxy)-propionic acid as a novel series of G protein-coupled receptor 40 agonists.

Song F, Lu S, Gunnet J, Xu JZ, Wines P, Proost J, Liang Y, Baumann C, Lenhard J, Murray WV, Demarest KT, Kuo GH. Song F, et al. Among authors: xu jz. J Med Chem. 2007 Jun 14;50(12):2807-17. doi: 10.1021/jm070130j. Epub 2007 May 15. J Med Chem. 2007. PMID: 17500511

6

Parallel synthesis and SAR study of novel oxa-steroids as potent and selective progesterone receptor antagonists.

Kang FA, Guan J, Jain N, Allan G, Linton O, Tannenbaum P, Chen X, Xu J, Zhu P, Gunnet J, Demarest K, Lundeen S, Sui Z. Kang FA, et al. Bioorg Med Chem Lett. 2007 May 1;17(9):2531-4. doi: 10.1016/j.bmcl.2007.02.013. Epub 2007 Feb 8. Bioorg Med Chem Lett. 2007. PMID: 17317167

7

Improvement of dyslipidemia, insulin sensitivity, and energy balance by a peroxisome proliferator-activated receptor alpha agonist.

Chen X, Matthews J, Zhou L, Pelton P, Liang Y, Xu J, Yang M, Cryan E, Rybczynski P, Demarest K. Chen X, et al. Metabolism. 2008 Nov;57(11):1516-25. doi: 10.1016/j.metabol.2008.06.005. Metabolism. 2008. PMID: 18940388

8

Synthesis and SAR study of novel pseudo-steroids as potent and selective progesterone receptor antagonists.

Jain N, Allan G, Linton O, Tannenbaum P, Chen X, Xu J, Zhu P, Gunnet J, Demarest K, Lundeen S, Murray W, Sui Z. Jain N, et al. Bioorg Med Chem Lett. 2009 Jul 15;19(14):3977-80. doi: 10.1016/j.bmcl.2009.01.095. Epub 2009 Jan 31. Bioorg Med Chem Lett. 2009. PMID: 19217285

9

Discovery of a dihydropyrimidine series of molecules that selectively mimic the biological actions of calcitonin.

Matthews JM, Liotta F, Hageman W, Rivero RA, Westover L, Yang M, Xu J, Demarest K. Matthews JM, et al. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1155-9. doi: 10.1016/j.bmcl.2003.12.071. Bioorg Med Chem Lett. 2004. PMID: 14980655

10

New progesterone receptor antagonists: phosphorus-containing 11beta-aryl-substituted steroids.

Jiang W, Allan G, Fiordeliso JJ, Linton O, Tannenbaum P, Xu J, Zhu P, Gunnet J, Demarest K, Lundeen S, Sui Z. Jiang W, et al. Bioorg Med Chem. 2006 Oct 1;14(19):6726-32. doi: 10.1016/j.bmc.2006.05.066. Epub 2006 Jun 27. Bioorg Med Chem. 2006. PMID: 16806946

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