Hughes SH - Search Results

1

Potential anti-AIDS naphthalenesulfonic acid derivatives. Synthesis and inhibition of HIV-1 induced cytopathogenesis and HIV-1 and HIV-2 reverse transcriptase activities.

Tan GT, Wickramasinghe A, Verma S, Singh R, Hughes SH, Pezzuto JM, Baba M, Mohan P. Tan GT, et al. Among authors: hughes sh. J Med Chem. 1992 Dec 25;35(26):4846-53. doi: 10.1021/jm00104a010. J Med Chem. 1992. PMID: 1282569

2

HIV-1 and HIV-2 reverse transcriptases: a comparative study of sensitivity to inhibition by selected natural products.

Tan GT, Miller JF, Kinghorn AD, Hughes SH, Pezzuto JM. Tan GT, et al. Among authors: hughes sh. Biochem Biophys Res Commun. 1992 May 29;185(1):370-8. doi: 10.1016/s0006-291x(05)80995-7. Biochem Biophys Res Commun. 1992. PMID: 1376118

3

The effects of cysteine mutations on the catalytic activities of the reverse transcriptase of human immunodeficiency virus type-1.

Loya S, Tal R, Hughes SH, Hizi A. Loya S, et al. Among authors: hughes sh. J Biol Chem. 1992 Jul 15;267(20):13879-83. J Biol Chem. 1992. PMID: 1378433 Free article.

4

The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.

Kashman Y, Gustafson KR, Fuller RW, Cardellina JH 2nd, McMahon JB, Currens MJ, Buckheit RW Jr, Hughes SH, Cragg GM, Boyd MR. Kashman Y, et al. Among authors: hughes sh. J Med Chem. 1992 Jul 24;35(15):2735-43. doi: 10.1021/jm00093a004. J Med Chem. 1992. PMID: 1379639

5

Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase.

Tan GT, Pezzuto JM, Kinghorn AD, Hughes SH. Tan GT, et al. Among authors: hughes sh. J Nat Prod. 1991 Jan-Feb;54(1):143-54. doi: 10.1021/np50073a012. J Nat Prod. 1991. PMID: 1710653

6

Psychotrine and its O-methyl ether are selective inhibitors of human immunodeficiency virus-1 reverse transcriptase.

Tan GT, Kinghorn AD, Hughes SH, Pezzuto JM. Tan GT, et al. Among authors: hughes sh. J Biol Chem. 1991 Dec 15;266(35):23529-36. J Biol Chem. 1991. PMID: 1721050 Free article.

7

Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance.

Tantillo C, Ding J, Jacobo-Molina A, Nanni RG, Boyer PL, Hughes SH, Pauwels R, Andries K, Janssen PA, Arnold E. Tantillo C, et al. Among authors: hughes sh. J Mol Biol. 1994 Oct 28;243(3):369-87. doi: 10.1006/jmbi.1994.1665. J Mol Biol. 1994. PMID: 7525966 Review.

8

Sulfonic acid polymers are potent inhibitors of HIV-1 induced cytopathogenicity and the reverse transcriptases of both HIV-1 and HIV-2.

Tan GT, Wickramasinghe A, Verma S, Hughes SH, Pezzuto JM, Baba M, Mohan P. Tan GT, et al. Among authors: hughes sh. Biochim Biophys Acta. 1993 Apr 30;1181(2):183-8. doi: 10.1016/0925-4439(93)90109-e. Biochim Biophys Acta. 1993. PMID: 7683207

9

Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (+/-)-calanolide A and its enantiomers.

Flavin MT, Rizzo JD, Khilevich A, Kucherenko A, Sheinkman AK, Vilaychack V, Lin L, Chen W, Greenwood EM, Pengsuparp T, Pezzuto JM, Hughes SH, Flavin TM, Cibulski M, Boulanger WA, Shone RL, Xu ZQ. Flavin MT, et al. Among authors: hughes sh. J Med Chem. 1996 Mar 15;39(6):1303-13. doi: 10.1021/jm950797i. J Med Chem. 1996. PMID: 8632437

10

Specific inhibition of human immunodeficiency virus type 1 reverse transcriptase mediated by soulattrolide, a coumarin isolated from the latex of calophyllum teysmannii.

Pengsuparp T, Serit M, Hughes SH, Soejarto DD, Pezzuto JM. Pengsuparp T, et al. Among authors: hughes sh. J Nat Prod. 1996 Sep;59(9):839-42. doi: 10.1021/np960399y. J Nat Prod. 1996. PMID: 8864237

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