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Polymorphic variants of insulin-like growth factor I (IGF-I) receptor and phosphoinositide 3-kinase genes affect IGF-I plasma levels and human longevity: cues for an evolutionarily conserved mechanism of life span control.
Bonafè M, Barbieri M, Marchegiani F, Olivieri F, Ragno E, Giampieri C, Mugianesi E, Centurelli M, Franceschi C, Paolisso G. Bonafè M, et al. Among authors: franceschi c. J Clin Endocrinol Metab. 2003 Jul;88(7):3299-304. doi: 10.1210/jc.2002-021810. J Clin Endocrinol Metab. 2003. PMID: 12843179
The -174 C/G locus affects in vitro/in vivo IL-6 production during aging.
Olivieri F, Bonafè M, Cavallone L, Giovagnetti S, Marchegiani F, Cardelli M, Mugianesi E, Giampieri C, Moresi R, Stecconi R, Lisa R, Franceschi C. Olivieri F, et al. Among authors: franceschi c. Exp Gerontol. 2002 Jan-Mar;37(2-3):309-14. doi: 10.1016/s0531-5565(01)00197-8. Exp Gerontol. 2002. PMID: 11772517
Genetic analysis of Paraoxonase (PON1) locus reveals an increased frequency of Arg192 allele in centenarians.
Bonafè M, Marchegiani F, Cardelli M, Olivieri F, Cavallone L, Giovagnetti S, Pieri C, Marra M, Antonicelli R, Troiano L, Gueresi P, Passeri G, Berardelli M, Paolisso G, Barbieri M, Tesei S, Lisa R, De Benedictis G, Franceschi C. Bonafè M, et al. Among authors: franceschi c. Eur J Hum Genet. 2002 May;10(5):292-6. doi: 10.1038/sj.ejhg.5200806. Eur J Hum Genet. 2002. PMID: 12082503
Chronic inflammation and the effect of IGF-I on muscle strength and power in older persons.
Barbieri M, Ferrucci L, Ragno E, Corsi A, Bandinelli S, Bonafè M, Olivieri F, Giovagnetti S, Franceschi C, Guralnik JM, Paolisso G. Barbieri M, et al. Among authors: franceschi c. Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E481-7. doi: 10.1152/ajpendo.00319.2002. Epub 2002 Nov 5. Am J Physiol Endocrinol Metab. 2003. PMID: 12419777 Free article.
Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes.
Zhang J, Asin-Cayuela J, Fish J, Michikawa Y, Bonafe M, Olivieri F, Passarino G, De Benedictis G, Franceschi C, Attardi G. Zhang J, et al. Among authors: franceschi c. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1116-21. doi: 10.1073/pnas.242719399. Epub 2003 Jan 21. Proc Natl Acad Sci U S A. 2003. PMID: 12538859 Free PMC article.
1,035 results