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Page 1
In vitro evaluation of 213Bi-rituximab versus external gamma irradiation for the treatment of B-CLL patients: relative biological efficacy with respect to apoptosis induction and chromosomal damage.
Vandenbulcke K, De Vos F, Offner F, Philippé J, Apostolidis C, Molinet R, Nikula TK, Bacher K, de Gelder V, Vral A, Lahorte C, Thierens H, Dierckx RA, Slegers G. Vandenbulcke K, et al. Among authors: nikula tk. Eur J Nucl Med Mol Imaging. 2003 Oct;30(10):1357-64. doi: 10.1007/s00259-003-1228-8. Epub 2003 Jul 3. Eur J Nucl Med Mol Imaging. 2003. PMID: 12845484
Cell death triggered by alpha-emitting 213Bi-immunoconjugates in HSC45-M2 gastric cancer cells is different from apoptotic cell death.
Seidl C, Schröck H, Seidenschwang S, Beck R, Schmid E, Abend M, Becker KF, Apostolidis C, Nikula TK, Kremmer E, Schwaiger M, Senekowitsch-Schmidtke R. Seidl C, et al. Among authors: nikula tk. Eur J Nucl Med Mol Imaging. 2005 Mar;32(3):274-85. doi: 10.1007/s00259-004-1653-3. Epub 2004 Oct 2. Eur J Nucl Med Mol Imaging. 2005. PMID: 15791436
Alpha-emitting bismuth cyclohexylbenzyl DTPA constructs of recombinant humanized anti-CD33 antibodies: pharmacokinetics, bioactivity, toxicity and chemistry.
Nikula TK, McDevitt MR, Finn RD, Wu C, Kozak RW, Garmestani K, Brechbiel MW, Curcio MJ, Pippin CG, Tiffany-Jones L, Geerlings MW Sr, Apostolidis C, Molinet R, Geerlings MW Jr, Gansow OA, Scheinberg DA. Nikula TK, et al. J Nucl Med. 1999 Jan;40(1):166-76. J Nucl Med. 1999. PMID: 9935073 Free article.
Highly specific tumor binding of a 213Bi-labeled monoclonal antibody against mutant E-cadherin suggests its usefulness for locoregional alpha-radioimmunotherapy of diffuse-type gastric cancer.
Senekowitsch-Schmidtke R, Schuhmacher C, Becker KF, Nikula TK, Seidl C, Becker I, Miederer M, Apostolidis C, Adam C, Huber R, Kremmer E, Fischer K, Schwaiger M. Senekowitsch-Schmidtke R, et al. Among authors: nikula tk. Cancer Res. 2001 Apr 1;61(7):2804-8. Cancer Res. 2001. PMID: 11306447
Comparison of the radiotoxicity of two alpha-particle-emitting immunoconjugates, terbium-149 and bismuth-213, directed against a tumor-specific, exon 9 deleted (d9) E-cadherin adhesion protein.
Miederer M, Seidl C, Beyer GJ, Charlton DE, Vranjes-Duric S, Comor JJ, Huber R, Nikula T, Apostolidis C, Schuhmacher C, Becker KF, Senekowitsch-Schmidtke R. Miederer M, et al. Radiat Res. 2003 May;159(5):612-20. doi: 10.1667/0033-7587(2003)159[0612:cotrot]2.0.co;2. Radiat Res. 2003. PMID: 12710872
Radiolabeled anti-CD33 monoclonal antibody M195 for myeloid leukemias.
Jurcic JG, Caron PC, Nikula TK, Papadopoulos EB, Finn RD, Gansow OA, Miller WH Jr, Geerlings MW, Warrell RP Jr, Larson SM, et al. Jurcic JG, et al. Among authors: nikula tk. Cancer Res. 1995 Dec 1;55(23 Suppl):5908s-5910s. Cancer Res. 1995. PMID: 7493368 Clinical Trial.
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