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A natural product ligand of the oxysterol receptor, liver X receptor.
Bramlett KS, Houck KA, Borchert KM, Dowless MS, Kulanthaivel P, Zhang Y, Beyer TP, Schmidt R, Thomas JS, Michael LF, Barr R, Montrose C, Eacho PI, Cao G, Burris TP. Bramlett KS, et al. Among authors: eacho pi. J Pharmacol Exp Ther. 2003 Oct;307(1):291-6. doi: 10.1124/jpet.103.052852. Epub 2003 Jul 31. J Pharmacol Exp Ther. 2003. PMID: 12893846
Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis.
Cao G, Liang Y, Broderick CL, Oldham BA, Beyer TP, Schmidt RJ, Zhang Y, Stayrook KR, Suen C, Otto KA, Miller AR, Dai J, Foxworthy P, Gao H, Ryan TP, Jiang XC, Burris TP, Eacho PI, Etgen GJ. Cao G, et al. Among authors: eacho pi. J Biol Chem. 2003 Jan 10;278(2):1131-6. doi: 10.1074/jbc.M210208200. Epub 2002 Oct 31. J Biol Chem. 2003. PMID: 12414791 Free article.
A chemical switch regulates fibrate specificity for peroxisome proliferator-activated receptor alpha (PPARalpha ) versus liver X receptor.
Thomas J, Bramlett KS, Montrose C, Foxworthy P, Eacho PI, McCann D, Cao G, Kiefer A, McCowan J, Yu KL, Grese T, Chin WW, Burris TP, Michael LF. Thomas J, et al. Among authors: eacho pi. J Biol Chem. 2003 Jan 24;278(4):2403-10. doi: 10.1074/jbc.M209629200. Epub 2002 Nov 18. J Biol Chem. 2003. PMID: 12441342 Free article.
Coadministration of a liver X receptor agonist and a peroxisome proliferator activator receptor-alpha agonist in Mice: effects of nuclear receptor interplay on high-density lipoprotein and triglyceride metabolism in vivo.
Beyer TP, Schmidt RJ, Foxworthy P, Zhang Y, Dai J, Bensch WR, Kauffman RF, Gao H, Ryan TP, Jiang XC, Karathanasis SK, Eacho PI, Cao G. Beyer TP, et al. Among authors: eacho pi. J Pharmacol Exp Ther. 2004 Jun;309(3):861-8. doi: 10.1124/jpet.103.064535. Epub 2004 Feb 11. J Pharmacol Exp Ther. 2004. PMID: 14960661
Phospholipid transfer protein is regulated by liver X receptors in vivo.
Cao G, Beyer TP, Yang XP, Schmidt RJ, Zhang Y, Bensch WR, Kauffman RF, Gao H, Ryan TP, Liang Y, Eacho PI, Jiang XC. Cao G, et al. Among authors: eacho pi. J Biol Chem. 2002 Oct 18;277(42):39561-5. doi: 10.1074/jbc.M207187200. Epub 2002 Aug 9. J Biol Chem. 2002. PMID: 12177004 Free article.
61 results