LaFerla FM - Search Results

1

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction.

Oddo S, Caccamo A, Shepherd JD, Murphy MP, Golde TE, Kayed R, Metherate R, Mattson MP, Akbari Y, LaFerla FM. Oddo S, et al. Among authors: laferla fm. Neuron. 2003 Jul 31;39(3):409-21. doi: 10.1016/s0896-6273(03)00434-3. Neuron. 2003. PMID: 12895417 Free article.

2

Presenilin-1 immunoreactivity is localized intracellularly in Alzheimer's disease brain, but not detected in amyloid plaques.

Weber LL, Leissring MA, Yang AJ, Glabe CG, Cribbs DH, LaFerla FM. Weber LL, et al. Among authors: laferla fm. Exp Neurol. 1997 Jan;143(1):37-44. doi: 10.1006/exnr.1996.6348. Exp Neurol. 1997. PMID: 9000444

3

Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice.

Leissring MA, Akbari Y, Fanger CM, Cahalan MD, Mattson MP, LaFerla FM. Leissring MA, et al. Among authors: laferla fm. J Cell Biol. 2000 May 15;149(4):793-8. doi: 10.1083/jcb.149.4.793. J Cell Biol. 2000. PMID: 10811821 Free PMC article.

4

A physiologic signaling role for the gamma -secretase-derived intracellular fragment of APP.

Leissring MA, Murphy MP, Mead TR, Akbari Y, Sugarman MC, Jannatipour M, Anliker B, Müller U, Saftig P, De Strooper B, Wolfe MS, Golde TE, LaFerla FM. Leissring MA, et al. Among authors: laferla fm. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4697-702. doi: 10.1073/pnas.072033799. Epub 2002 Mar 26. Proc Natl Acad Sci U S A. 2002. PMID: 11917117 Free PMC article.

5

Inclusion body myositis-like phenotype induced by transgenic overexpression of beta APP in skeletal muscle.

Sugarman MC, Yamasaki TR, Oddo S, Echegoyen JC, Murphy MP, Golde TE, Jannatipour M, Leissring MA, LaFerla FM. Sugarman MC, et al. Among authors: laferla fm. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6334-9. doi: 10.1073/pnas.082545599. Epub 2002 Apr 23. Proc Natl Acad Sci U S A. 2002. PMID: 11972038 Free PMC article.

6

Calcium dyshomeostasis and intracellular signalling in Alzheimer's disease.

LaFerla FM. LaFerla FM. Nat Rev Neurosci. 2002 Nov;3(11):862-72. doi: 10.1038/nrn960. Nat Rev Neurosci. 2002. PMID: 12415294 Review. No abstract available.

7

Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

Oddo S, Caccamo A, Kitazawa M, Tseng BP, LaFerla FM. Oddo S, et al. Among authors: laferla fm. Neurobiol Aging. 2003 Dec;24(8):1063-70. doi: 10.1016/j.neurobiolaging.2003.08.012. Neurobiol Aging. 2003. PMID: 14643377

8

Dysregulated IP3 signaling in cortical neurons of knock-in mice expressing an Alzheimer's-linked mutation in presenilin1 results in exaggerated Ca2+ signals and altered membrane excitability.

Stutzmann GE, Caccamo A, LaFerla FM, Parker I. Stutzmann GE, et al. Among authors: laferla fm. J Neurosci. 2004 Jan 14;24(2):508-13. doi: 10.1523/JNEUROSCI.4386-03.2004. J Neurosci. 2004. PMID: 14724250 Free PMC article.

9

Enhanced neuronal excitability in the absence of neurodegeneration induces cerebellar ataxia.

Shakkottai VG, Chou CH, Oddo S, Sailer CA, Knaus HG, Gutman GA, Barish ME, LaFerla FM, Chandy KG. Shakkottai VG, et al. Among authors: laferla fm. J Clin Invest. 2004 Feb;113(4):582-90. doi: 10.1172/JCI20216. J Clin Invest. 2004. PMID: 14966567 Free PMC article.

10

Live discussion: how the other half lives - or the what, how, and where, of the AbetaPP intracellular domain.

Bishop G, Coleman P, Crutcher K, David D, Kinoshita J, LaFerla F, Leissring M, Shepherd J, Therianos S, Wang R, Wilson A, Zhu M. Bishop G, et al. J Alzheimers Dis. 2004 Apr;6(2):193-9. doi: 10.3233/jad-2004-6212. J Alzheimers Dis. 2004. PMID: 15171221 No abstract available.

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