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Melanin-concentrating hormone is a critical mediator of the leptin-deficient phenotype.
Segal-Lieberman G, Bradley RL, Kokkotou E, Carlson M, Trombly DJ, Wang X, Bates S, Myers MG Jr, Flier JS, Maratos-Flier E. Segal-Lieberman G, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):10085-90. doi: 10.1073/pnas.1633636100. Epub 2003 Aug 1. Proc Natl Acad Sci U S A. 2003. PMID: 12897241 Free PMC article.
Mice with MCH ablation resist diet-induced obesity through strain-specific mechanisms.
Kokkotou E, Jeon JY, Wang X, Marino FE, Carlson M, Trombly DJ, Maratos-Flier E. Kokkotou E, et al. Among authors: wang x. Am J Physiol Regul Integr Comp Physiol. 2005 Jul;289(1):R117-24. doi: 10.1152/ajpregu.00861.2004. Epub 2005 Feb 24. Am J Physiol Regul Integr Comp Physiol. 2005. PMID: 15731402 Free article.
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