Sedelies KA - Search Results

1

Novel mechanisms of apoptosis induced by histone deacetylase inhibitors.

Peart MJ, Tainton KM, Ruefli AA, Dear AE, Sedelies KA, O'Reilly LA, Waterhouse NJ, Trapani JA, Johnstone RW. Peart MJ, et al. Among authors: sedelies ka. Cancer Res. 2003 Aug 1;63(15):4460-71. Cancer Res. 2003. PMID: 12907619

2

A central role for Bid in granzyme B-induced apoptosis.

Waterhouse NJ, Sedelies KA, Browne KA, Wowk ME, Newbold A, Sutton VR, Clarke CJ, Oliaro J, Lindemann RK, Bird PI, Johnstone RW, Trapani JA. Waterhouse NJ, et al. Among authors: sedelies ka. J Biol Chem. 2005 Feb 11;280(6):4476-82. doi: 10.1074/jbc.M410985200. Epub 2004 Dec 1. J Biol Chem. 2005. PMID: 15574417 Free article.

3

Functional dissociation of DeltaPsim and cytochrome c release defines the contribution of mitochondria upstream of caspase activation during granzyme B-induced apoptosis.

Waterhouse NJ, Sedelies KA, Sutton VR, Pinkoski MJ, Thia KY, Johnstone R, Bird PI, Green DR, Trapani JA. Waterhouse NJ, et al. Among authors: sedelies ka. Cell Death Differ. 2006 Apr;13(4):607-18. doi: 10.1038/sj.cdd.4401772. Cell Death Differ. 2006. PMID: 16167065

4

Blocking granule-mediated death by primary human NK cells requires both protection of mitochondria and inhibition of caspase activity.

Sedelies KA, Ciccone A, Clarke CJ, Oliaro J, Sutton VR, Scott FL, Silke J, Susanto O, Green DR, Johnstone RW, Bird PI, Trapani JA, Waterhouse NJ. Sedelies KA, et al. Cell Death Differ. 2008 Apr;15(4):708-17. doi: 10.1038/sj.cdd.4402300. Epub 2008 Jan 18. Cell Death Differ. 2008. PMID: 18202705

5

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis.

Susanto O, Stewart SE, Voskoboinik I, Brasacchio D, Hagn M, Ellis S, Asquith S, Sedelies KA, Bird PI, Waterhouse NJ, Trapani JA. Susanto O, et al. Among authors: sedelies ka. Cell Death Differ. 2013 Sep;20(9):1183-93. doi: 10.1038/cdd.2013.59. Epub 2013 Jun 7. Cell Death Differ. 2013. PMID: 23744295 Free PMC article.

6

Cytotoxic lymphocytes; instigators of dramatic target cell death.

Waterhouse NJ, Clarke CJ, Sedelies KA, Teng MW, Trapani JA. Waterhouse NJ, et al. Among authors: sedelies ka. Biochem Pharmacol. 2004 Sep 15;68(6):1033-40. doi: 10.1016/j.bcp.2004.05.043. Biochem Pharmacol. 2004. PMID: 15313398 Review.

7

Role of Bid-induced mitochondrial outer membrane permeabilization in granzyme B-induced apoptosis.

Waterhouse NJ, Sedelies KA, Trapani JA. Waterhouse NJ, et al. Among authors: sedelies ka. Immunol Cell Biol. 2006 Feb;84(1):72-8. doi: 10.1111/j.1440-1711.2005.01416.x. Immunol Cell Biol. 2006. PMID: 16405654 Review.

8

Cytotoxic T lymphocyte-induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis.

Waterhouse NJ, Sutton VR, Sedelies KA, Ciccone A, Jenkins M, Turner SJ, Bird PI, Trapani JA. Waterhouse NJ, et al. Among authors: sedelies ka. J Cell Biol. 2006 Apr 10;173(1):133-44. doi: 10.1083/jcb.200510072. J Cell Biol. 2006. PMID: 16606695 Free PMC article.

9

Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.

Sutton VR, Davis JE, Cancilla M, Johnstone RW, Ruefli AA, Sedelies K, Browne KA, Trapani JA. Sutton VR, et al. Among authors: sedelies k. J Exp Med. 2000 Nov 20;192(10):1403-14. doi: 10.1084/jem.192.10.1403. J Exp Med. 2000. PMID: 11085743 Free PMC article.

10

Granzyme B triggers a prolonged pressure to die in Bcl-2 overexpressing cells, defining a window of opportunity for effective treatment with ABT-737.

Sutton VR, Sedelies K, Dewson G, Christensen ME, Bird PI, Johnstone RW, Kluck RM, Trapani JA, Waterhouse NJ. Sutton VR, et al. Cell Death Dis. 2012 Jul 5;3(7):e344. doi: 10.1038/cddis.2012.73. Cell Death Dis. 2012. PMID: 22764103 Free PMC article.

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