Knight ZA - Search Results

1

Phosphospecific proteolysis for mapping sites of protein phosphorylation.

Knight ZA, Schilling B, Row RH, Kenski DM, Gibson BW, Shokat KM. Knight ZA, et al. Nat Biotechnol. 2003 Sep;21(9):1047-54. doi: 10.1038/nbt863. Epub 2003 Aug 17. Nat Biotechnol. 2003. PMID: 12923550

2

Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold.

Knight ZA, Chiang GG, Alaimo PJ, Kenski DM, Ho CB, Coan K, Abraham RT, Shokat KM. Knight ZA, et al. Bioorg Med Chem. 2004 Sep 1;12(17):4749-59. doi: 10.1016/j.bmc.2004.06.022. Bioorg Med Chem. 2004. PMID: 15358300

3

Targeting the gatekeeper residue in phosphoinositide 3-kinases.

Alaimo PJ, Knight ZA, Shokat KM. Alaimo PJ, et al. Among authors: knight za. Bioorg Med Chem. 2005 Apr 15;13(8):2825-36. doi: 10.1016/j.bmc.2005.02.021. Bioorg Med Chem. 2005. PMID: 15781393

4

Features of selective kinase inhibitors.

Knight ZA, Shokat KM. Knight ZA, et al. Chem Biol. 2005 Jun;12(6):621-37. doi: 10.1016/j.chembiol.2005.04.011. Chem Biol. 2005. PMID: 15975507 Review.

5

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling.

Knight ZA, Gonzalez B, Feldman ME, Zunder ER, Goldenberg DD, Williams O, Loewith R, Stokoe D, Balla A, Toth B, Balla T, Weiss WA, Williams RL, Shokat KM. Knight ZA, et al. Cell. 2006 May 19;125(4):733-47. doi: 10.1016/j.cell.2006.03.035. Epub 2006 Apr 27. Cell. 2006. PMID: 16647110 Free PMC article.

6

Effect of combined DNA repair inhibition and G2 checkpoint inhibition on cell cycle progression after DNA damage.

Sturgeon CM, Knight ZA, Shokat KM, Roberge M. Sturgeon CM, et al. Among authors: knight za. Mol Cancer Ther. 2006 Apr;5(4):885-92. doi: 10.1158/1535-7163.MCT-05-0358. Mol Cancer Ther. 2006. PMID: 16648558

7

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma.

Fan QW, Knight ZA, Goldenberg DD, Yu W, Mostov KE, Stokoe D, Shokat KM, Weiss WA. Fan QW, et al. Among authors: knight za. Cancer Cell. 2006 May;9(5):341-9. doi: 10.1016/j.ccr.2006.03.029. Cancer Cell. 2006. PMID: 16697955 Free PMC article.

8

To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front.

Van Keymeulen A, Wong K, Knight ZA, Govaerts C, Hahn KM, Shokat KM, Bourne HR. Van Keymeulen A, et al. Among authors: knight za. J Cell Biol. 2006 Jul 31;174(3):437-45. doi: 10.1083/jcb.200604113. Epub 2006 Jul 24. J Cell Biol. 2006. PMID: 16864657 Free PMC article.

9

Phosphatidylinositol 4-kinase IIIbeta regulates the transport of ceramide between the endoplasmic reticulum and Golgi.

Tóth B, Balla A, Ma H, Knight ZA, Shokat KM, Balla T. Tóth B, et al. Among authors: knight za. J Biol Chem. 2006 Nov 24;281(47):36369-77. doi: 10.1074/jbc.M604935200. Epub 2006 Sep 26. J Biol Chem. 2006. PMID: 17003043 Free article.

10

Chemical genetics: where genetics and pharmacology meet.

Knight ZA, Shokat KM. Knight ZA, et al. Cell. 2007 Feb 9;128(3):425-30. doi: 10.1016/j.cell.2007.01.021. Cell. 2007. PMID: 17289560 Free article.

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