Shokat KM - Search Results

1

Phosphospecific proteolysis for mapping sites of protein phosphorylation.

Knight ZA, Schilling B, Row RH, Kenski DM, Gibson BW, Shokat KM. Knight ZA, et al. Among authors: shokat km. Nat Biotechnol. 2003 Sep;21(9):1047-54. doi: 10.1038/nbt863. Epub 2003 Aug 17. Nat Biotechnol. 2003. PMID: 12923550

2

Engineering a "methionine clamp" into Src family kinases enhances specificity toward unnatural ATP analogues.

Ulrich SM, Kenski DM, Shokat KM. Ulrich SM, et al. Among authors: shokat km. Biochemistry. 2003 Jul 8;42(26):7915-21. doi: 10.1021/bi030042a. Biochemistry. 2003. PMID: 12834343

3

Targets of the cyclin-dependent kinase Cdk1.

Ubersax JA, Woodbury EL, Quang PN, Paraz M, Blethrow JD, Shah K, Shokat KM, Morgan DO. Ubersax JA, et al. Among authors: shokat km. Nature. 2003 Oct 23;425(6960):859-64. doi: 10.1038/nature02062. Nature. 2003. PMID: 14574415

4

Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold.

Knight ZA, Chiang GG, Alaimo PJ, Kenski DM, Ho CB, Coan K, Abraham RT, Shokat KM. Knight ZA, et al. Among authors: shokat km. Bioorg Med Chem. 2004 Sep 1;12(17):4749-59. doi: 10.1016/j.bmc.2004.06.022. Bioorg Med Chem. 2004. PMID: 15358300

5

Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor.

Kung C, Kenski DM, Dickerson SH, Howson RW, Kuyper LF, Madhani HD, Shokat KM. Kung C, et al. Among authors: shokat km. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3587-92. doi: 10.1073/pnas.0407170102. Epub 2005 Feb 28. Proc Natl Acad Sci U S A. 2005. PMID: 15738404 Free PMC article.

6

Targeting the gatekeeper residue in phosphoinositide 3-kinases.

Alaimo PJ, Knight ZA, Shokat KM. Alaimo PJ, et al. Among authors: shokat km. Bioorg Med Chem. 2005 Apr 15;13(8):2825-36. doi: 10.1016/j.bmc.2005.02.021. Bioorg Med Chem. 2005. PMID: 15781393

7

A second-site suppressor strategy for chemical genetic analysis of diverse protein kinases.

Zhang C, Kenski DM, Paulson JL, Bonshtien A, Sessa G, Cross JV, Templeton DJ, Shokat KM. Zhang C, et al. Among authors: shokat km. Nat Methods. 2005 Jun;2(6):435-41. doi: 10.1038/nmeth764. Nat Methods. 2005. PMID: 15908922

8

Features of selective kinase inhibitors.

Knight ZA, Shokat KM. Knight ZA, et al. Among authors: shokat km. Chem Biol. 2005 Jun;12(6):621-37. doi: 10.1016/j.chembiol.2005.04.011. Chem Biol. 2005. PMID: 15975507 Review.

9

Chemical genetic engineering of G protein-coupled receptor kinase 2.

Kenski DM, Zhang C, von Zastrow M, Shokat KM. Kenski DM, et al. Among authors: shokat km. J Biol Chem. 2005 Oct 14;280(41):35051-61. doi: 10.1074/jbc.M507594200. Epub 2005 Aug 4. J Biol Chem. 2005. PMID: 16081410 Free article.

10

Selective kinase inhibition by exploiting differential pathway sensitivity.

Kung C, Kenski DM, Krukenberg K, Madhani HD, Shokat KM. Kung C, et al. Among authors: shokat km. Chem Biol. 2006 Apr;13(4):399-407. doi: 10.1016/j.chembiol.2006.02.004. Chem Biol. 2006. PMID: 16632252 Free PMC article.

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