Minshull CA - Search Results

1

Imidazo[1,2-a]pyridines: a potent and selective class of cyclin-dependent kinase inhibitors identified through structure-based hybridisation.

Anderson M, Beattie JF, Breault GA, Breed J, Byth KF, Culshaw JD, Ellston RP, Green S, Minshull CA, Norman RA, Pauptit RA, Stanway J, Thomas AP, Jewsbury PJ. Anderson M, et al. Among authors: minshull ca. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3021-6. doi: 10.1016/s0960-894x(03)00638-3. Bioorg Med Chem Lett. 2003. PMID: 12941325

2

Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 1: identification and optimisation of substituted 4,6-bis anilino pyrimidines.

Beattie JF, Breault GA, Ellston RP, Green S, Jewsbury PJ, Midgley CJ, Naven RT, Minshull CA, Pauptit RA, Tucker JA, Pease JE. Beattie JF, et al. Among authors: minshull ca. Bioorg Med Chem Lett. 2003 Sep 15;13(18):2955-60. doi: 10.1016/s0960-894x(03)00202-6. Bioorg Med Chem Lett. 2003. PMID: 12941311

3

Cyclin-dependent kinase 4 inhibitors as a treatment for cancer. Part 2: identification and optimisation of substituted 2,4-bis anilino pyrimidines.

Breault GA, Ellston RP, Green S, James SR, Jewsbury PJ, Midgley CJ, Pauptit RA, Minshull CA, Tucker JA, Pease JE. Breault GA, et al. Among authors: minshull ca. Bioorg Med Chem Lett. 2003 Sep 15;13(18):2961-6. doi: 10.1016/s0960-894x(03)00203-8. Bioorg Med Chem Lett. 2003. PMID: 12941312

4

Imidazo[1,2-b]pyridazines: a potent and selective class of cyclin-dependent kinase inhibitors.

Byth KF, Cooper N, Culshaw JD, Heaton DW, Oakes SE, Minshull CA, Norman RA, Pauptit RA, Tucker JA, Breed J, Pannifer A, Rowsell S, Stanway JJ, Valentine AL, Thomas AP. Byth KF, et al. Among authors: minshull ca. Bioorg Med Chem Lett. 2004 May 3;14(9):2249-52. doi: 10.1016/j.bmcl.2004.02.008. Bioorg Med Chem Lett. 2004. PMID: 15081018

5

Structure-based design of protein tyrosine phosphatase-1B inhibitors.

Black E, Breed J, Breeze AL, Embrey K, Garcia R, Gero TW, Godfrey L, Kenny PW, Morley AD, Minshull CA, Pannifer AD, Read J, Rees A, Russell DJ, Toader D, Tucker J. Black E, et al. Among authors: minshull ca. Bioorg Med Chem Lett. 2005 May 16;15(10):2503-7. doi: 10.1016/j.bmcl.2005.03.068. Bioorg Med Chem Lett. 2005. PMID: 15863305

6

Crystal structure of human thymidine phosphorylase in complex with a small molecule inhibitor.

Norman RA, Barry ST, Bate M, Breed J, Colls JG, Ernill RJ, Luke RW, Minshull CA, McAlister MS, McCall EJ, McMiken HH, Paterson DS, Timms D, Tucker JA, Pauptit RA. Norman RA, et al. Among authors: minshull ca. Structure. 2004 Jan;12(1):75-84. doi: 10.1016/j.str.2003.11.018. Structure. 2004. PMID: 14725767 Free article.

7

Crystal structure of human MMP9 in complex with a reverse hydroxamate inhibitor.

Rowsell S, Hawtin P, Minshull CA, Jepson H, Brockbank SM, Barratt DG, Slater AM, McPheat WL, Waterson D, Henney AM, Pauptit RA. Rowsell S, et al. Among authors: minshull ca. J Mol Biol. 2002 May 24;319(1):173-81. doi: 10.1016/S0022-2836(02)00262-0. J Mol Biol. 2002. PMID: 12051944

8

Kinetic and structural characteristics of the inhibition of enoyl (acyl carrier protein) reductase by triclosan.

Ward WH, Holdgate GA, Rowsell S, McLean EG, Pauptit RA, Clayton E, Nichols WW, Colls JG, Minshull CA, Jude DA, Mistry A, Timms D, Camble R, Hales NJ, Britton CJ, Taylor IW. Ward WH, et al. Among authors: minshull ca. Biochemistry. 1999 Sep 21;38(38):12514-25. doi: 10.1021/bi9907779. Biochemistry. 1999. PMID: 10493822

9

Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains.

Gerhardt S, Hassall G, Hawtin P, McCall E, Flavell L, Minshull C, Hargreaves D, Ting A, Pauptit RA, Parker AE, Abbott WM. Gerhardt S, et al. J Mol Biol. 2007 Nov 2;373(4):891-902. doi: 10.1016/j.jmb.2007.07.047. Epub 2007 Aug 2. J Mol Biol. 2007. PMID: 17897672

10

Study of the interaction of the medium chain mu 2 subunit of the clathrin-associated adapter protein complex 2 with cytotoxic T-lymphocyte antigen 4 and CD28.

Follows ER, McPheat JC, Minshull C, Moore NC, Pauptit RA, Rowsell S, Stacey CL, Stanway JJ, Taylor IW, Abbott WM. Follows ER, et al. Biochem J. 2001 Oct 15;359(Pt 2):427-34. doi: 10.1042/0264-6021:3590427. Biochem J. 2001. PMID: 11583591 Free PMC article.

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