Smith DG - Search Results

1

6-heteroaryl-pyrazolo[3,4-b]pyridines: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Gaiba A, Naylor A, Rawlings AD, Slingsby BP, Smith DG, Takle AK, Ward RW. Witherington J, et al. Among authors: smith dg. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3059-62. doi: 10.1016/s0960-894x(03)00646-2. Bioorg Med Chem Lett. 2003. PMID: 12941333

2

5-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Garland SL, Hickey DM, Ife RJ, Liddle J, Saunders M, Smith DG, Ward RW. Witherington J, et al. Among authors: smith dg. Bioorg Med Chem Lett. 2003 May 5;13(9):1577-80. doi: 10.1016/s0960-894x(03)00134-3. Bioorg Med Chem Lett. 2003. PMID: 12699759

3

5-aryl-pyrazolo[3,4-b]pyridazines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Haigh D, Hickey DM, Ife RJ, Rawlings AD, Slingsby BP, Smith DG, Ward RW. Witherington J, et al. Among authors: smith dg. Bioorg Med Chem Lett. 2003 May 5;13(9):1581-4. doi: 10.1016/s0960-894x(03)00135-5. Bioorg Med Chem Lett. 2003. PMID: 12699760

4

6-aryl-pyrazolo[3,4-b]pyridines: potent inhibitors of glycogen synthase kinase-3 (GSK-3).

Witherington J, Bordas V, Gaiba A, Garton NS, Naylor A, Rawlings AD, Slingsby BP, Smith DG, Takle AK, Ward RW. Witherington J, et al. Among authors: smith dg. Bioorg Med Chem Lett. 2003 Sep 15;13(18):3055-7. doi: 10.1016/s0960-894x(03)00645-0. Bioorg Med Chem Lett. 2003. PMID: 12941332

5

Pyridone derivatives as potent and selective VLA-4 integrin antagonists.

Witherington J, Bordas V, Gaiba A, Green PM, Naylor A, Parr N, Smith DG, Takle AK, Ward RW. Witherington J, et al. Among authors: smith dg. Bioorg Med Chem Lett. 2006 Apr 15;16(8):2256-9. doi: 10.1016/j.bmcl.2006.01.025. Epub 2006 Feb 7. Bioorg Med Chem Lett. 2006. PMID: 16455247

6

Pyridone derivatives as potent, orally bioavailable VLA-4 integrin antagonists.

Witherington J, Blaney EL, Bordas V, Elliott RL, Gaiba A, Garton N, Green PM, Naylor A, Smith DG, Spalding DJ, Takle AK, Ward RW. Witherington J, et al. Among authors: smith dg. Bioorg Med Chem Lett. 2006 Nov 1;16(21):5538-41. doi: 10.1016/j.bmcl.2006.08.044. Epub 2006 Aug 22. Bioorg Med Chem Lett. 2006. PMID: 16931004

7

3-Anilino-4-arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3).

Smith DG, Buffet M, Fenwick AE, Haigh D, Ife RJ, Saunders M, Slingsby BP, Stacey R, Ward RW. Smith DG, et al. Bioorg Med Chem Lett. 2001 Mar 12;11(5):635-9. doi: 10.1016/s0960-894x(00)00721-6. Bioorg Med Chem Lett. 2001. PMID: 11266159

8

The inhibition of human cytomegalovirus (hCMV) protease by hydroxylamine derivatives.

Smith DG, Gribble AD, Haigh D, Ife RJ, Lavery P, Skett P, Slingsby BP, Stacey R, Ward RW, West A. Smith DG, et al. Bioorg Med Chem Lett. 1999 Nov 1;9(21):3137-42. doi: 10.1016/s0960-894x(99)00539-9. Bioorg Med Chem Lett. 1999. PMID: 10560740

9

Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription.

Coghlan MP, Culbert AA, Cross DA, Corcoran SL, Yates JW, Pearce NJ, Rausch OL, Murphy GJ, Carter PS, Roxbee Cox L, Mills D, Brown MJ, Haigh D, Ward RW, Smith DG, Murray KJ, Reith AD, Holder JC. Coghlan MP, et al. Among authors: smith dg. Chem Biol. 2000 Oct;7(10):793-803. doi: 10.1016/s1074-5521(00)00025-9. Chem Biol. 2000. PMID: 11033082

10

The structure of phosphorylated GSK-3beta complexed with a peptide, FRATtide, that inhibits beta-catenin phosphorylation.

Bax B, Carter PS, Lewis C, Guy AR, Bridges A, Tanner R, Pettman G, Mannix C, Culbert AA, Brown MJ, Smith DG, Reith AD. Bax B, et al. Among authors: smith dg. Structure. 2001 Dec;9(12):1143-52. doi: 10.1016/s0969-2126(01)00679-7. Structure. 2001. PMID: 11738041 Free article.

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