Gerngross TU - Search Results

1

Production of complex human glycoproteins in yeast.

Hamilton SR, Bobrowicz P, Bobrowicz B, Davidson RC, Li H, Mitchell T, Nett JH, Rausch S, Stadheim TA, Wischnewski H, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: gerngross tu. Science. 2003 Aug 29;301(5637):1244-6. doi: 10.1126/science.1088166. Science. 2003. PMID: 12947202

2

Humanization of yeast to produce complex terminally sialylated glycoproteins.

Hamilton SR, Davidson RC, Sethuraman N, Nett JH, Jiang Y, Rios S, Bobrowicz P, Stadheim TA, Li H, Choi BK, Hopkins D, Wischnewski H, Roser J, Mitchell T, Strawbridge RR, Hoopes J, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: gerngross tu. Science. 2006 Sep 8;313(5792):1441-3. doi: 10.1126/science.1130256. Science. 2006. PMID: 16960007

3

Use of combinatorial genetic libraries to humanize N-linked glycosylation in the yeast Pichia pastoris.

Choi BK, Bobrowicz P, Davidson RC, Hamilton SR, Kung DH, Li H, Miele RG, Nett JH, Wildt S, Gerngross TU. Choi BK, et al. Among authors: gerngross tu. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5022-7. doi: 10.1073/pnas.0931263100. Epub 2003 Apr 17. Proc Natl Acad Sci U S A. 2003. PMID: 12702754 Free PMC article.

4

Characterization of N-linked glycosylation on recombinant glycoproteins produced in Pichia pastoris using ESI-MS and MALDI-TOF.

Gong B, Cukan M, Fisher R, Li H, Stadheim TA, Gerngross T. Gong B, et al. Methods Mol Biol. 2009;534:213-23. doi: 10.1007/978-1-59745-022-5_16. Methods Mol Biol. 2009. PMID: 19277549 Review.

5

Glycosylation engineering in yeast: the advent of fully humanized yeast.

Hamilton SR, Gerngross TU. Hamilton SR, et al. Among authors: gerngross tu. Curr Opin Biotechnol. 2007 Oct;18(5):387-92. doi: 10.1016/j.copbio.2007.09.001. Epub 2007 Oct 24. Curr Opin Biotechnol. 2007. PMID: 17951046 Review.

6

A combinatorial genetic library approach to target heterologous glycosylation enzymes to the endoplasmic reticulum or the Golgi apparatus of Pichia pastoris.

Nett JH, Stadheim TA, Li H, Bobrowicz P, Hamilton SR, Davidson RC, Choi BK, Mitchell T, Bobrowicz B, Rittenhour A, Wildt S, Gerngross TU. Nett JH, et al. Among authors: gerngross tu. Yeast. 2011 Mar;28(3):237-52. doi: 10.1002/yea.1835. Epub 2011 Jan 6. Yeast. 2011. PMID: 21360735

7

Intact {alpha}-1,2-endomannosidase is a typical type II membrane protein.

Hamilton SR, Li H, Wischnewski H, Prasad A, Kerley-Hamilton JS, Mitchell T, Walling AJ, Davidson RC, Wildt S, Gerngross TU. Hamilton SR, et al. Among authors: gerngross tu. Glycobiology. 2005 Jun;15(6):615-24. doi: 10.1093/glycob/cwi045. Epub 2005 Jan 26. Glycobiology. 2005. PMID: 15677381

8

Optimization of humanized IgGs in glycoengineered Pichia pastoris.

Li H, Sethuraman N, Stadheim TA, Zha D, Prinz B, Ballew N, Bobrowicz P, Choi BK, Cook WJ, Cukan M, Houston-Cummings NR, Davidson R, Gong B, Hamilton SR, Hoopes JP, Jiang Y, Kim N, Mansfield R, Nett JH, Rios S, Strawbridge R, Wildt S, Gerngross TU. Li H, et al. Among authors: gerngross tu. Nat Biotechnol. 2006 Feb;24(2):210-5. doi: 10.1038/nbt1178. Epub 2006 Jan 22. Nat Biotechnol. 2006. PMID: 16429149

9

N-linked glycan characterization of heterologous proteins.

Li H, Miele RG, Mitchell TI, Gerngross TU. Li H, et al. Among authors: gerngross tu. Methods Mol Biol. 2007;389:139-50. doi: 10.1007/978-1-59745-456-8_10. Methods Mol Biol. 2007. PMID: 17951640

10

Use of high-performance anion exchange chromatography with pulsed amperometric detection for O-glycan determination in yeast.

Stadheim TA, Li H, Kett W, Burnina IN, Gerngross TU. Stadheim TA, et al. Among authors: gerngross tu. Nat Protoc. 2008;3(6):1026-31. doi: 10.1038/nprot.2008.76. Nat Protoc. 2008. PMID: 18546597

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