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Irinotecan plus leucovorin-modulated 5-fluorouracil I.V. bolus every other week may be a suitable therapeutic option also for elderly patients with metastatic colorectal carcinoma.
Comella P, Farris A, Lorusso V, Palmeri S, Maiorino L, De Lucia L, Buzzi F, Mancarella S, De Vita F, Gambardella A. Comella P, et al. Among authors: gambardella a. Br J Cancer. 2003 Sep 15;89(6):992-6. doi: 10.1038/sj.bjc.6601214. Br J Cancer. 2003. PMID: 12966414 Free PMC article. Clinical Trial.
A tailored regimen including capecitabine and oxaliplatin for treating elderly patients with metastatic colorectal carcinoma Southern Italy Cooperative Oncology Group trial 0108.
Comella P, Gambardella A, Farris A, Maiorino L, Natale D, Massidda B, Casaretti R, Tafuto S, Lorusso V, Leo S; Southern Italy Cooperative Oncology Group. Comella P, et al. Among authors: gambardella a. Crit Rev Oncol Hematol. 2005 Feb;53(2):133-9. doi: 10.1016/j.critrevonc.2004.10.008. Crit Rev Oncol Hematol. 2005. PMID: 15661564 Clinical Trial.
Capecitabine plus oxaliplatin for the first-line treatment of elderly patients with metastatic colorectal carcinoma: final results of the Southern Italy Cooperative Oncology Group Trial 0108.
Comella P, Natale D, Farris A, Gambardella A, Maiorino L, Massidda B, Casaretti R, Tafuto S, Lorusso V, Leo S, Cannone M. Comella P, et al. Among authors: gambardella a. Cancer. 2005 Jul 15;104(2):282-9. doi: 10.1002/cncr.21167. Cancer. 2005. PMID: 15948167 Free article. Clinical Trial.
Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients: results of the Southern Italy Cooperative Oncology study 0401.
Comella P, Massidda B, Filippelli G, Farris A, Natale D, Barberis G, Maiorino L, Palmeri S, Cannone M, Condemi G; Southern Italy Cooperative Oncology Group. Comella P, et al. J Cancer Res Clin Oncol. 2009 Feb;135(2):217-26. doi: 10.1007/s00432-008-0454-7. Epub 2008 Aug 22. J Cancer Res Clin Oncol. 2009. PMID: 18719941 Clinical Trial.
Efficacy of the combination of cisplatin with either gemcitabine and vinorelbine or gemcitabine and paclitaxel in the treatment of locally advanced or metastatic non-small-cell lung cancer: a phase III randomised trial of the Southern Italy Cooperative Oncology Group (SICOG 0101).
Comella P, Filippelli G, De Cataldis G, Massidda B, Frasci G, Maiorino L, Putzu C, Mancarella S, Palmeri S, Cioffi R, Roselli M, Buzzi F, Milia V, Gambardella A, Natale D, Bianco M, Ghiani M, Masullo P; Southern Italy Cooperative Oncology Group. Comella P, et al. Among authors: gambardella a. Ann Oncol. 2007 Feb;18(2):324-30. doi: 10.1093/annonc/mdl396. Epub 2006 Oct 27. Ann Oncol. 2007. PMID: 17071935 Free article. Clinical Trial.
Intra-patient alternated dose escalation of paclitaxel and gemcitabine versus paclitaxel followed by fixed dose rate infusion of gemcitabine in fit elderly non-small cell lung cancer patients. A Southern Italy Cooperative Oncology Group randomised phase II trial.
Comella P, Putzu C, Massidda B, Condemi G, De Cataldis G, Barbato E, Gambardella A, Avallone A, Franco L; Southern Italy Cooperative Oncology Group. Comella P, et al. Among authors: gambardella a. Lung Cancer. 2007 May;56(2):263-71. doi: 10.1016/j.lungcan.2006.12.015. Epub 2007 Feb 12. Lung Cancer. 2007. PMID: 17298853 Clinical Trial.
Comparison of the safety and efficacy of paclitaxel plus gemcitabine combination in young and elderly patients with locally advanced or metastatic non-small cell lung cancer. A retrospective analysis of the Southern Italy Cooperative Oncology Group trials.
Comella P, Gambardella A, Frasci G, Avallone A, Costanzo R; SICOG investigators. Comella P, et al. Among authors: gambardella a. Crit Rev Oncol Hematol. 2008 Feb;65(2):164-71. doi: 10.1016/j.critrevonc.2007.06.014. Epub 2007 Aug 16. Crit Rev Oncol Hematol. 2008. PMID: 17702595 Clinical Trial.
740 results