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Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone.
Murphy MP, Echtay KS, Blaikie FH, Asin-Cayuela J, Cocheme HM, Green K, Buckingham JA, Taylor ER, Hurrell F, Hughes G, Miwa S, Cooper CE, Svistunenko DA, Smith RA, Brand MD. Murphy MP, et al. Among authors: smith ra. J Biol Chem. 2003 Dec 5;278(49):48534-45. doi: 10.1074/jbc.M308529200. Epub 2003 Sep 12. J Biol Chem. 2003. PMID: 12972420 Free article.
Antioxidant properties of MitoTEMPOL and its hydroxylamine.
Trnka J, Blaikie FH, Logan A, Smith RA, Murphy MP. Trnka J, et al. Among authors: smith ra. Free Radic Res. 2009 Jan;43(1):4-12. doi: 10.1080/10715760802582183. Free Radic Res. 2009. PMID: 19058062 Free PMC article.
Delivery of bioactive molecules to mitochondria in vivo.
Smith RA, Porteous CM, Gane AM, Murphy MP. Smith RA, et al. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5407-12. doi: 10.1073/pnas.0931245100. Epub 2003 Apr 15. Proc Natl Acad Sci U S A. 2003. PMID: 12697897 Free PMC article.
Specific targeting of a DNA-alkylating reagent to mitochondria. Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide.
James AM, Blaikie FH, Smith RA, Lightowlers RN, Smith PM, Murphy MP. James AM, et al. Among authors: smith ra, smith pm. Eur J Biochem. 2003 Jul;270(13):2827-36. doi: 10.1046/j.1432-1033.2003.03660.x. Eur J Biochem. 2003. PMID: 12823553 Free article.
1,952 results