Hamada A - Search Results

1

Interaction of imatinib mesilate with human P-glycoprotein.

Hamada A, Miyano H, Watanabe H, Saito H. Hamada A, et al. J Pharmacol Exp Ther. 2003 Nov;307(2):824-8. doi: 10.1124/jpet.103.055574. Epub 2003 Sep 15. J Pharmacol Exp Ther. 2003. PMID: 12975485

2

Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells.

Hirayama C, Watanabe H, Nakashima R, Nanbu T, Hamada A, Kuniyasu A, Nakayama H, Kawaguchi T, Saito H. Hirayama C, et al. Among authors: hamada a. Pharm Res. 2008 Apr;25(4):827-35. doi: 10.1007/s11095-007-9376-3. Epub 2007 Oct 13. Pharm Res. 2008. PMID: 17934801

3

Role of P-glycoprotein in accumulation and cytotoxicity of amrubicin and amrubicinol in MDR1 gene-transfected LLC-PK1 cells and human A549 lung adenocarcinoma cells.

Hira A, Watanabe H, Maeda Y, Yokoo K, Sanematsu E, Fujii J, Sasaki J, Hamada A, Saito H. Hira A, et al. Among authors: hamada a. Biochem Pharmacol. 2008 Feb 15;75(4):973-80. doi: 10.1016/j.bcp.2007.10.023. Epub 2007 Oct 30. Biochem Pharmacol. 2008. PMID: 18054347

4

P-glycoprotein mediates efflux transport of darunavir in human intestinal Caco-2 and ABCB1 gene-transfected renal LLC-PK1 cell lines.

Fujimoto H, Higuchi M, Watanabe H, Koh Y, Ghosh AK, Mitsuya H, Tanoue N, Hamada A, Saito H. Fujimoto H, et al. Among authors: hamada a. Biol Pharm Bull. 2009 Sep;32(9):1588-93. doi: 10.1248/bpb.32.1588. Biol Pharm Bull. 2009. PMID: 19721237 Free PMC article.

5

Role of P-glycoprotein in the efflux of raltegravir from human intestinal cells and CD4+ T-cells as an interaction target for anti-HIV agents.

Hashiguchi Y, Hamada A, Shinohara T, Tsuchiya K, Jono H, Saito H. Hashiguchi Y, et al. Among authors: hamada a. Biochem Biophys Res Commun. 2013 Sep 20;439(2):221-7. doi: 10.1016/j.bbrc.2013.08.054. Epub 2013 Aug 24. Biochem Biophys Res Commun. 2013. PMID: 23981805

6

Distinct interaction of nilotinib and imatinib with P-Glycoprotein in intracellular accumulation and cytotoxicity in CML Cell Line K562 cells.

Yamakawa Y, Hamada A, Uchida T, Sato D, Yuki M, Hayashi M, Kawaguchi T, Saito H. Yamakawa Y, et al. Among authors: hamada a. Biol Pharm Bull. 2014;37(8):1330-5. doi: 10.1248/bpb.b14-00254. Biol Pharm Bull. 2014. PMID: 25087954 Free article.

7

Pharmacokinetic impact of SLCO1A2 polymorphisms on imatinib disposition in patients with chronic myeloid leukemia.

Yamakawa Y, Hamada A, Shuto T, Yuki M, Uchida T, Kai H, Kawaguchi T, Saito H. Yamakawa Y, et al. Among authors: hamada a. Clin Pharmacol Ther. 2011 Jul;90(1):157-63. doi: 10.1038/clpt.2011.102. Epub 2011 Jun 1. Clin Pharmacol Ther. 2011. PMID: 21633340 Free article.

8

Involvement of up-regulation of hepatic breast cancer resistance protein in decreased plasma concentration of 7-ethyl-10-hydroxycamptothecin (SN-38) by coadministration of S-1 in rats.

Yokoo K, Hamada A, Watanabe H, Matsuzaki T, Imai T, Fujimoto H, Masa K, Imai T, Saito H. Yokoo K, et al. Among authors: hamada a. Drug Metab Dispos. 2007 Sep;35(9):1511-7. doi: 10.1124/dmd.107.015164. Epub 2007 May 30. Drug Metab Dispos. 2007. PMID: 17537871

9

Relationship between an effective dose of imatinib, body surface area, and trough drug levels in patients with chronic myeloid leukemia.

Kawaguchi T, Hamada A, Hirayama C, Nakashima R, Nambu T, Yamakawa Y, Watanabe H, Horikawa K, Mitsuya H, Saito H. Kawaguchi T, et al. Among authors: hamada a. Int J Hematol. 2009 Jun;89(5):642-8. doi: 10.1007/s12185-009-0315-4. Epub 2009 Apr 25. Int J Hematol. 2009. PMID: 19396513 Free article. Clinical Trial.

10

Contribution of BCR-ABL-independent activation of ERK1/2 to acquired imatinib resistance in K562 chronic myeloid leukemia cells.

Nambu T, Araki N, Nakagawa A, Kuniyasu A, Kawaguchi T, Hamada A, Saito H. Nambu T, et al. Among authors: hamada a. Cancer Sci. 2010 Jan;101(1):137-42. doi: 10.1111/j.1349-7006.2009.01365.x. Epub 2009 Sep 14. Cancer Sci. 2010. PMID: 19843070 Free PMC article.

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