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The mannose-specific plant lectins from Cymbidium hybrid and Epipactis helleborine and the (N-acetylglucosamine)n-specific plant lectin from Urtica dioica are potent and selective inhibitors of human immunodeficiency virus and cytomegalovirus replication in vitro.
Balzarini J, Neyts J, Schols D, Hosoya M, Van Damme E, Peumans W, De Clercq E. Balzarini J, et al. Among authors: peumans w. Antiviral Res. 1992 Jun;18(2):191-207. doi: 10.1016/0166-3542(92)90038-7. Antiviral Res. 1992. PMID: 1329650
Mannose-specific plant lectins from the Amaryllidaceae family qualify as efficient microbicides for prevention of human immunodeficiency virus infection.
Balzarini J, Hatse S, Vermeire K, Princen K, Aquaro S, Perno CF, De Clercq E, Egberink H, Vanden Mooter G, Peumans W, Van Damme E, Schols D. Balzarini J, et al. Among authors: peumans w. Antimicrob Agents Chemother. 2004 Oct;48(10):3858-70. doi: 10.1128/AAC.48.10.3858-3870.2004. Antimicrob Agents Chemother. 2004. PMID: 15388446 Free PMC article.
Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV GP120: a new therapeutic concept to hit the achilles heel of HIV.
Balzarini J, Van Laethem K, Hatse S, Froeyen M, Peumans W, Van Damme E, Schols D. Balzarini J, et al. Among authors: peumans w. J Biol Chem. 2005 Dec 9;280(49):41005-14. doi: 10.1074/jbc.M508801200. Epub 2005 Sep 23. J Biol Chem. 2005. PMID: 16183648 Free article.
Hippeastrum hybrid and Galanthus nivalis agglutinin) or prokaryotes (i.e. cyanovirin-N) inhibit human immunodeficiency virus (HIV) replication and select for drug-resistant viruses that show profound deletion of N-glycosylation sites in the GP120 envelope (Balzarini, J., Van Laet …
Hippeastrum hybrid and Galanthus nivalis agglutinin) or prokaryotes (i.e. cyanovirin-N) inhibit human immunodeficiency virus (HIV) replicati …
Lectins as plant defense proteins.
Peumans WJ, Van Damme EJ. Peumans WJ, et al. Plant Physiol. 1995 Oct;109(2):347-52. doi: 10.1104/pp.109.2.347. Plant Physiol. 1995. PMID: 7480335 Free PMC article. Review. No abstract available.
269 results