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Analogues of the dioxolanes dexoxadrol and etoxadrol as potential phencyclidine-like agents. Synthesis and structure-activity relationships.
J Med Chem. 1992 Apr 17;35(8):1323-9. doi: 10.1021/jm00086a001.
J Med Chem. 1992.
PMID: 1349351
Enantiomeric and diastereomeric dioxadrols: behavioral, biochemical and chemical determination of the configuration necessary for phencyclidine-like properties.
Jacobson AE, Harrison EA Jr, Mattson MV, Rafferty MF, Rice KC, Woods JH, Winger G, Solomon RE, Lessor RA, Silverton JV.
Jacobson AE, et al. Among authors: harrison ea jr.
J Pharmacol Exp Ther. 1987 Oct;243(1):110-7.
J Pharmacol Exp Ther. 1987.
PMID: 2822892
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Evidence for separation of anesthetic activity from prototypic phencyclidine action in drug discrimination by molecular modification of dioxadrol, a phencyclidine-like dissociative anesthetic.
Harrison EA Jr, Rafferty MF, Rice KC, Creveling CR, Winger GD, Woods JH, Jacobson AE.
Harrison EA Jr, et al.
NIDA Res Monogr. 1984;55:90-6.
NIDA Res Monogr. 1984.
PMID: 6100507
No abstract available.
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