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Discovery of 4-benzoyl-1-[(4-methoxy-1H- pyrrolo[2,3-b]pyridin-3-yl)oxoacetyl]-2- (R)-methylpiperazine (BMS-378806): a novel HIV-1 attachment inhibitor that interferes with CD4-gp120 interactions.
Wang T, Zhang Z, Wallace OB, Deshpande M, Fang H, Yang Z, Zadjura LM, Tweedie DL, Huang S, Zhao F, Ranadive S, Robinson BS, Gong YF, Ricarrdi K, Spicer TP, Deminie C, Rose R, Wang HG, Blair WS, Shi PY, Lin PF, Colonno RJ, Meanwell NA. Wang T, et al. Among authors: rose r. J Med Chem. 2003 Sep 25;46(20):4236-9. doi: 10.1021/jm034082o. J Med Chem. 2003. PMID: 13678401
Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions.
Guo Q, Ho HT, Dicker I, Fan L, Zhou N, Friborg J, Wang T, McAuliffe BV, Wang HG, Rose RE, Fang H, Scarnati HT, Langley DR, Meanwell NA, Abraham R, Colonno RJ, Lin PF. Guo Q, et al. Among authors: rose re. J Virol. 2003 Oct;77(19):10528-36. doi: 10.1128/jvi.77.19.10528-10536.2003. J Virol. 2003. PMID: 12970437 Free PMC article.
A small molecule HIV-1 inhibitor that targets the HIV-1 envelope and inhibits CD4 receptor binding.
Lin PF, Blair W, Wang T, Spicer T, Guo Q, Zhou N, Gong YF, Wang HG, Rose R, Yamanaka G, Robinson B, Li CB, Fridell R, Deminie C, Demers G, Yang Z, Zadjura L, Meanwell N, Colonno R. Lin PF, et al. Among authors: rose r. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):11013-8. doi: 10.1073/pnas.1832214100. Epub 2003 Aug 20. Proc Natl Acad Sci U S A. 2003. PMID: 12930892 Free PMC article.
Characterization of siamycin I, a human immunodeficiency virus fusion inhibitor.
Lin PF, Samanta H, Bechtold CM, Deminie CA, Patick AK, Alam M, Riccardi K, Rose RE, White RJ, Colonno RJ. Lin PF, et al. Among authors: rose re. Antimicrob Agents Chemother. 1996 Jan;40(1):133-8. doi: 10.1128/AAC.40.1.133. Antimicrob Agents Chemother. 1996. PMID: 8787894 Free PMC article.
Inhibition of hepatitis B virus polymerase by entecavir.
Langley DR, Walsh AW, Baldick CJ, Eggers BJ, Rose RE, Levine SM, Kapur AJ, Colonno RJ, Tenney DJ. Langley DR, et al. Among authors: rose re. J Virol. 2007 Apr;81(8):3992-4001. doi: 10.1128/JVI.02395-06. Epub 2007 Jan 31. J Virol. 2007. PMID: 17267485 Free PMC article.
2,114 results