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Insulin-like growth factor-I-stimulated insulin receptor substrate-1 negatively regulates Src homology 2 domain-containing protein-tyrosine phosphatase substrate-1 function in vascular smooth muscle cells.
Radhakrishnan Y, Busby WH Jr, Shen X, Maile LA, Clemmons DR. Radhakrishnan Y, et al. Among authors: busby wh jr. J Biol Chem. 2010 May 21;285(21):15682-95. doi: 10.1074/jbc.M109.092270. Epub 2010 Mar 5. J Biol Chem. 2010. PMID: 20207740 Free PMC article.
Inhibition of insulin-like growth factor binding protein 5 proteolysis in articular cartilage and joint fluid results in enhanced concentrations of insulin-like growth factor 1 and is associated with improved osteoarthritis.
Clemmons DR, Busby WH Jr, Garmong A, Schultz DR, Howell DS, Altman RD, Karr R. Clemmons DR, et al. Among authors: busby wh jr. Arthritis Rheum. 2002 Mar;46(3):694-703. doi: 10.1002/art.10222. Arthritis Rheum. 2002. PMID: 11920405 Free article.
43 results