Ornstein PL - Search Results

1

6-substituted decahydroisoquinoline-3-carboxylic acids as potent and selective conformationally constrained NMDA receptor antagonists.

Ornstein PL, Schoepp DD, Arnold MB, Augenstein NK, Lodge D, Millar JD, Chambers J, Campbell J, Paschal JW, Zimmerman DM, et al. Ornstein PL, et al. J Med Chem. 1992 Sep 18;35(19):3547-60. doi: 10.1021/jm00097a012. J Med Chem. 1992. PMID: 1404235

2

Analogues of the dioxolanes dexoxadrol and etoxadrol as potential phencyclidine-like agents. Synthesis and structure-activity relationships.

Thurkauf A, Mattson MV, Richardson S, Mirsadeghi S, Ornstein PL, Harrison EA Jr, Rice KC, Jacobson AE, Monn JA. Thurkauf A, et al. Among authors: ornstein pl. J Med Chem. 1992 Apr 17;35(8):1323-9. doi: 10.1021/jm00086a001. J Med Chem. 1992. PMID: 1349351

3

Synthesis and excitatory amino acid pharmacology of a series of heterocyclic-fused quinoxalinones and quinazolinones.

McQuaid LA, Smith EC, South KK, Mitch CH, Schoepp DD, True RA, Calligaro DO, O'Malley PJ, Lodge D, Ornstein PL. McQuaid LA, et al. Among authors: ornstein pl. J Med Chem. 1992 Sep 4;35(18):3319-24. doi: 10.1021/jm00096a002. J Med Chem. 1992. PMID: 1382133

4

NMDA antagonist activity of (+/-)-(2SR,4RS)-4-(1H-tetrazol-5-ylmethyl)piperidine-2-carboxylic acid resides with the (-)-2R,4S-isomer.

Ornstein PL, Schoepp DD, Arnold MB, Jones ND, Deeter JB, Lodge D, Leander JD. Ornstein PL, et al. J Med Chem. 1992 Aug 21;35(17):3111-5. doi: 10.1021/jm00095a004. J Med Chem. 1992. PMID: 1387167

5

Protection against amphetamine-induced neurotoxicity toward striatal dopamine neurons in rodents by LY274614, an excitatory amino acid antagonist.

Fuller RW, Hemrick-Luecke SK, Ornstein PL. Fuller RW, et al. Among authors: ornstein pl. Neuropharmacology. 1992 Oct;31(10):1027-32. doi: 10.1016/0028-3908(92)90104-w. Neuropharmacology. 1992. PMID: 1436384

6

4-(Tetrazolylalkyl)piperidine-2-carboxylic acids. Potent and selective N-methyl-D-aspartic acid receptor antagonists with a short duration of action.

Ornstein PL, Schoepp DD, Arnold MB, Leander JD, Lodge D, Paschal JW, Elzey T. Ornstein PL, et al. J Med Chem. 1991 Jan;34(1):90-7. doi: 10.1021/jm00105a016. J Med Chem. 1991. PMID: 1825117

7

NMDA receptor antagonists suppress behaviors but not norepinephrine turnover or locus coeruleus unit activity induced by opiate withdrawal.

Rasmussen K, Fuller RW, Stockton ME, Perry KW, Swinford RM, Ornstein PL. Rasmussen K, et al. Among authors: ornstein pl. Eur J Pharmacol. 1991 May 2;197(1):9-16. doi: 10.1016/0014-2999(91)90358-w. Eur J Pharmacol. 1991. PMID: 1832640

8

Neuroprotectant effects of LY274614, a structurally novel systemically active competitive NMDA receptor antagonist.

Schoepp DD, Ornstein PL, Salhoff CR, Leander JD. Schoepp DD, et al. Among authors: ornstein pl. J Neural Transm Gen Sect. 1991;85(2):131-43. doi: 10.1007/BF01244705. J Neural Transm Gen Sect. 1991. PMID: 1834088

9

Pharmacological characterization of LY233053: a structurally novel tetrazole-substituted competitive N-methyl-D-aspartic acid antagonist with a short duration of action.

Schoepp DD, Ornstein PL, Leander JD, Lodge D, Salhoff CR, Zeman S, Zimmerman DM. Schoepp DD, et al. Among authors: ornstein pl. J Pharmacol Exp Ther. 1990 Dec;255(3):1301-8. J Pharmacol Exp Ther. 1990. PMID: 2148188

10

LY233053: a structurally novel, potent and selective competitive N-methyl-D-aspartate receptor antagonist.

Ornstein PL, Schoepp DD, Leander JD, Wong T, Zimmerman DM, Lodge D. Ornstein PL, et al. Prog Clin Biol Res. 1990;361:429-33. Prog Clin Biol Res. 1990. PMID: 2149764 No abstract available.

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