Kobayashi S - Search Results

1

Simplified approach for evaluation of hepatic drug-oxidizing capacity with a simultaneous measurement of caffeine and its primary demethylated metabolites in carbon tetrachloride-intoxicated rats.

Tanaka E, Ishikawa A, Yamamoto Y, Uchida E, Kobayashi S, Yasuhara H, Misawa S. Tanaka E, et al. Among authors: kobayashi s. Xenobiotica. 1992 May;22(5):535-41. doi: 10.3109/00498259209053116. Xenobiotica. 1992. PMID: 1413868

2

Trimethadione metabolism as a probe drug to estimate hepatic oxidizing capacity in rats.

Tanaka E, Ishikawa A, Kobayashi S, Yasuhara H, Misawa S, Kuroiwa Y. Tanaka E, et al. Among authors: kobayashi s. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993 Feb;104(2):205-7. doi: 10.1016/0742-8413(93)90025-g. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1993. PMID: 8098675 Review.

3

Trimethadione as a probe drug to estimate hepatic oxidizing capacity in humans.

Tanaka E, Ishikawa A, Abei M, Kobayashi S. Tanaka E, et al. Among authors: kobayashi s. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996 Nov;115(3):211-6. doi: 10.1016/s0742-8413(96)00102-8. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1996. PMID: 9375358 Review.

4

A simplified approach for evaluation of hepatic drug-oxidizing activity with a simultaneous determination of caffeine and trimethadione and their demethylated metabolites in rats with a selective cytochrome P-450 inducer.

Tanaka E, Ishikawa A, Yamamoto Y, Uchida E, Kobayashi S, Yasuhara H, Misawa S. Tanaka E, et al. Among authors: kobayashi s. Biopharm Drug Dispos. 1992 May;13(4):263-72. doi: 10.1002/bdd.2510130405. Biopharm Drug Dispos. 1992. PMID: 1600112

5

Simplified approach for determination of hepatic drug-oxidizing capacity using trimethadione metabolism as an indicator.

Tanaka E, Kobayashi S, Nakamura K, Uchida E, Yasuhara H. Tanaka E, et al. Among authors: kobayashi s. Biopharm Drug Dispos. 1989 Nov-Dec;10(6):617-20. doi: 10.1002/bdd.2510100611. Biopharm Drug Dispos. 1989. PMID: 2611361 Clinical Trial. No abstract available.

6

The effects of malotilate on hepatic drug metabolizing systems in different strains of rats.

Kai K, Kobayashi S, Uchida E, Sakai H, Tanaka E, Kurata N, Yasuhara H. Kai K, et al. Among authors: kobayashi s. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988;90(1):13-9. Comp Biochem Physiol C Comp Pharmacol Toxicol. 1988. PMID: 2904852

7

The effects of diltiazem on hepatic drug metabolizing enzymes in man using antipyrine, trimethadione and debrisoquine as model substrates.

Sakai H, Kobayashi S, Hamada K, Iida S, Akita H, Tanaka E, Uchida E, Yasuhara H. Sakai H, et al. Among authors: kobayashi s. Br J Clin Pharmacol. 1991 Mar;31(3):353-5. doi: 10.1111/j.1365-2125.1991.tb05543.x. Br J Clin Pharmacol. 1991. PMID: 2054276 Free PMC article.

8

Strain differences of antipyrine, trimethadione, and debrisoquine metabolism in female rats.

Tanaka E, Kobayashi S, Yasuhara H, Misawa S. Tanaka E, et al. Among authors: kobayashi s. Res Commun Chem Pathol Pharmacol. 1990 Aug;69(2):233-6. Res Commun Chem Pathol Pharmacol. 1990. PMID: 2396050 No abstract available.

9

Pharmacokinetic study of trimethadione and its metabolite in blood, liver and brain by microdialysis in conscious, unrestrained rats.

Kurata N, Inagaki M, Iwase M, Nishimura Y, Kiuchi Y, Yamazaki Y, Kobayashi S, Oguchi K, Uchida E, Yasuhara H. Kurata N, et al. Among authors: kobayashi s. Res Commun Mol Pathol Pharmacol. 1995 Jul;89(1):45-56. Res Commun Mol Pathol Pharmacol. 1995. PMID: 7582861

10

The effects of inhibitors and substrates of different types of cytochrome P450 isozymes on serum dimethadione/trimethadione ratio in rats in vivo.

Nishimura Y, Kurata N, Kobayashi S, Uchida E, Yasuhara H. Nishimura Y, et al. Among authors: kobayashi s. Res Commun Mol Pathol Pharmacol. 1995 Feb;87(2):145-54. Res Commun Mol Pathol Pharmacol. 1995. PMID: 7749652

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