Hayek T - Search Results

1

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells.

Plump AS, Smith JD, Hayek T, Aalto-Setälä K, Walsh A, Verstuyft JG, Rubin EM, Breslow JL. Plump AS, et al. Among authors: hayek t. Cell. 1992 Oct 16;71(2):343-53. doi: 10.1016/0092-8674(92)90362-g. Cell. 1992. PMID: 1423598

2

Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice. Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles.

Aalto-Setälä K, Fisher EA, Chen X, Chajek-Shaul T, Hayek T, Zechner R, Walsh A, Ramakrishnan R, Ginsberg HN, Breslow JL. Aalto-Setälä K, et al. Among authors: hayek t. J Clin Invest. 1992 Nov;90(5):1889-900. doi: 10.1172/JCI116066. J Clin Invest. 1992. PMID: 1430212 Free PMC article.

3

Expression of the human apolipoprotein A-I gene in transgenic mice alters high density lipoprotein (HDL) particle size distribution and diminishes selective uptake of HDL cholesteryl esters.

Chajek-Shaul T, Hayek T, Walsh A, Breslow JL. Chajek-Shaul T, et al. Among authors: hayek t. Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6731-5. doi: 10.1073/pnas.88.15.6731. Proc Natl Acad Sci U S A. 1991. PMID: 1907375 Free PMC article.

4

Accumulation of human apolipoprotein E in the plasma of transgenic mice.

Smith JD, Plump AS, Hayek T, Walsh A, Breslow JL. Smith JD, et al. Among authors: hayek t. J Biol Chem. 1990 Sep 5;265(25):14709-12. J Biol Chem. 1990. PMID: 2394690 Free article.

5

Decreased early atherosclerotic lesions in hypertriglyceridemic mice expressing cholesteryl ester transfer protein transgene.

Hayek T, Masucci-Magoulas L, Jiang X, Walsh A, Rubin E, Breslow JL, Tall AR. Hayek T, et al. J Clin Invest. 1995 Oct;96(4):2071-4. doi: 10.1172/JCI118255. J Clin Invest. 1995. PMID: 7560101 Free PMC article.

6

Overexpression of apolipoprotein CII causes hypertriglyceridemia in transgenic mice.

Shachter NS, Hayek T, Leff T, Smith JD, Rosenberg DW, Walsh A, Ramakrishnan R, Goldberg IJ, Ginsberg HN, Breslow JL. Shachter NS, et al. Among authors: hayek t. J Clin Invest. 1994 Apr;93(4):1683-90. doi: 10.1172/JCI117151. J Clin Invest. 1994. PMID: 8163669 Free PMC article.

7

Dietary fat increases high density lipoprotein (HDL) levels both by increasing the transport rates and decreasing the fractional catabolic rates of HDL cholesterol ester and apolipoprotein (Apo) A-I. Presentation of a new animal model and mechanistic studies in human Apo A-I transgenic and control mice.

Hayek T, Ito Y, Azrolan N, Verdery RB, Aalto-Setälä K, Walsh A, Breslow JL. Hayek T, et al. J Clin Invest. 1993 Apr;91(4):1665-71. doi: 10.1172/JCI116375. J Clin Invest. 1993. PMID: 8473509 Free PMC article.

8

An interaction between the human cholesteryl ester transfer protein (CETP) and apolipoprotein A-I genes in transgenic mice results in a profound CETP-mediated depression of high density lipoprotein cholesterol levels.

Hayek T, Chajek-Shaul T, Walsh A, Agellon LB, Moulin P, Tall AR, Breslow JL. Hayek T, et al. J Clin Invest. 1992 Aug;90(2):505-10. doi: 10.1172/JCI115887. J Clin Invest. 1992. PMID: 1644921 Free PMC article.

9

Probucol decreases apolipoprotein A-I transport rate and increases high density lipoprotein cholesteryl ester fractional catabolic rate in control and human apolipoprotein A-I transgenic mice.

Hayek T, Chajek-Shaul T, Walsh A, Azrolan N, Breslow JL. Hayek T, et al. Arterioscler Thromb. 1991 Sep-Oct;11(5):1295-302. doi: 10.1161/01.atv.11.5.1295. Arterioscler Thromb. 1991. PMID: 1911715

10

Reduced high density lipoprotein cholesterol in human cholesteryl ester transfer protein transgenic mice.

Agellon LB, Walsh A, Hayek T, Moulin P, Jiang XC, Shelanski SA, Breslow JL, Tall AR. Agellon LB, et al. Among authors: hayek t. J Biol Chem. 1991 Jun 15;266(17):10796-801. J Biol Chem. 1991. PMID: 2040599 Free article.

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