Hwang SM - Search Results

1

Investigation of conformational specificity at GPIIb/IIIa: evaluation of conformationally constrained RGD peptides.

Peishoff CE, Ali FE, Bean JW, Calvo R, D'Ambrosio CA, Eggleston DS, Hwang SM, Kline TP, Koster PF, Nichols A, et al. Peishoff CE, et al. Among authors: hwang sm. J Med Chem. 1992 Oct 16;35(21):3962-9. doi: 10.1021/jm00099a026. J Med Chem. 1992. PMID: 1433203

2

Design and synthesis of a C7 mimetic for the predicted gamma-turn conformation found in several constrained RGD antagonists.

Callahan JF, Bean JW, Burgess JL, Eggleston DS, Hwang SM, Kopple KD, Koster PF, Nichols A, Peishoff CE, Samanen JM, et al. Callahan JF, et al. Among authors: hwang sm. J Med Chem. 1992 Oct 16;35(21):3970-2. doi: 10.1021/jm00099a027. J Med Chem. 1992. PMID: 1433204 No abstract available.

3

Conformationally constrained peptides and semipeptides derived from RGD as potent inhibitors of the platelet fibrinogen receptor and platelet aggregation.

Ali FE, Bennett DB, Calvo RR, Elliott JD, Hwang SM, Ku TW, Lago MA, Nichols AJ, Romoff TT, Shah DH, et al. Ali FE, et al. Among authors: hwang sm. J Med Chem. 1994 Mar 18;37(6):769-80. doi: 10.1021/jm00032a009. J Med Chem. 1994. PMID: 8145226

4

Potent, selective, orally active 3-oxo-1,4-benzodiazepine GPIIb/IIIa integrin antagonists.

Samanen JM, Ali FE, Barton LS, Bondinell WE, Burgess JL, Callahan JF, Calvo RR, Chen W, Chen L, Erhard K, Feuerstein G, Heys R, Hwang SM, Jakas DR, Keenan RM, Ku TW, Kwon C, Lee CP, Miller WH, Newlander KA, Nichols A, Parker M, Peishoff CE, Rhodes G, Ross S, Shu A, Simpson R, Takata D, Yellin TO, Uzsinskas I, Venslavsky JW, Yuan CK, Huffman WF. Samanen JM, et al. Among authors: hwang sm. J Med Chem. 1996 Dec 6;39(25):4867-70. doi: 10.1021/jm960558a. J Med Chem. 1996. PMID: 8960544 No abstract available.

5

Discovery of potent nonpeptide vitronectin receptor (alpha v beta 3) antagonists.

Keenan RM, Miller WH, Kwon C, Ali FE, Callahan JF, Calvo RR, Hwang SM, Kopple KD, Peishoff CE, Samanen JM, Wong AS, Yuan CK, Huffman WF. Keenan RM, et al. Among authors: hwang sm. J Med Chem. 1997 Jul 18;40(15):2289-92. doi: 10.1021/jm970205r. J Med Chem. 1997. PMID: 9240343 No abstract available.

6

Conformational preferences in a benzodiazepine series of potent nonpeptide fibrinogen receptor antagonists.

Keenan RM, Callahan JF, Samanen JM, Bondinell WE, Calvo RR, Chen L, DeBrosse C, Eggleston DS, Haltiwanger RC, Hwang SM, Jakas DR, Ku TW, Miller WH, Newlander KA, Nichols A, Parker MF, Southhall LS, Uzinskas I, Vasko-Moser JA, Venslavsky JW, Wong AS, Huffman WF. Keenan RM, et al. Among authors: hwang sm. J Med Chem. 1999 Feb 25;42(4):545-59. doi: 10.1021/jm980166z. J Med Chem. 1999. PMID: 10052962

7

Binding of [3H]-SK&F 107260 and [3H]-SB 214857 to purified integrin alphaIIbbeta3: evidence for a common binding site for cyclic arginyl-glycinyl-aspartic acid peptides and nonpeptides.

Wong A, Hwang SM, Johanson K, Samanen J, Bennett D, Landvatter SW, Chen W, Heys JR, Ali FE, Ku TW, Bondinell W, Nichols AJ, Powers DA, Stadel JM. Wong A, et al. Among authors: hwang sm. J Pharmacol Exp Ther. 1998 Apr;285(1):228-35. J Pharmacol Exp Ther. 1998. PMID: 9536015

8

Benzimidazole derivatives as arginine mimetics in 1,4-benzodiazepine nonpeptide vitronectin receptor (alpha v beta 3) antagonists.

Keenan RM, Miller WH, Lago MA, Ali FE, Bondinell WE, Callahan JF, Calvo RR, Cousins RD, Hwang SM, Jakas DR, Ku TW, Kwon C, Nguyen TT, Reader VA, Rieman DJ, Ross ST, Takata DT, Uzinskas IN, Yuan CC, Smith BR. Keenan RM, et al. Among authors: hwang sm. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3165-70. doi: 10.1016/s0960-894x(98)00555-1. Bioorg Med Chem Lett. 1998. PMID: 9873696

9

Cloning and characterization of a novel integrin beta3 subunit.

Kumar CS, James IE, Wong A, Mwangi V, Feild JA, Nuthulaganti P, Connor JR, Eichman C, Ali F, Hwang SM, Rieman DJ, Drake FH, Gowen M. Kumar CS, et al. Among authors: hwang sm. J Biol Chem. 1997 Jun 27;272(26):16390-7. doi: 10.1074/jbc.272.26.16390. J Biol Chem. 1997. PMID: 9195946 Free article.

10

Discovery of an imidazopyridine-containing 1,4-benzodiazepine nonpeptide vitronectin receptor (alpha v beta 3) antagonist with efficacy in a restenosis model.

Keenan RM, Lago MA, Miller WH, Ali FE, Cousins RD, Hall LB, Hwang SM, Jakas DR, Kwon C, Louden C, Nguyen TT, Ohlstein EH, Rieman DJ, Ross ST, Samanen JM, Smith BR, Stadel J, Takata DT, Vickery L, Yuan CC, Yue TL. Keenan RM, et al. Among authors: hwang sm. Bioorg Med Chem Lett. 1998 Nov 17;8(22):3171-6. doi: 10.1016/s0960-894x(98)00556-3. Bioorg Med Chem Lett. 1998. PMID: 9873697

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