Tyler PC - Search Results

1

Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction.

Evans GB, Furneaux RH, Tyler PC, Schramm VL. Evans GB, et al. Among authors: tyler pc. Org Lett. 2003 Oct 2;5(20):3639-40. doi: 10.1021/ol035293q. Org Lett. 2003. PMID: 14507192

2

Isozyme-specific transition state inhibitors for the trypanosomal nucleoside hydrolases.

Parkin DW, Limberg G, Tyler PC, Furneaux RH, Chen XY, Schramm VL. Parkin DW, et al. Among authors: tyler pc. Biochemistry. 1997 Mar 25;36(12):3528-34. doi: 10.1021/bi962319v. Biochemistry. 1997. PMID: 9132003

3

One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.

Miles RW, Tyler PC, Furneaux RH, Bagdassarian CK, Schramm VL. Miles RW, et al. Among authors: tyler pc. Biochemistry. 1998 Jun 16;37(24):8615-21. doi: 10.1021/bi980658d. Biochemistry. 1998. PMID: 9628722

4

Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases.

Li CM, Tyler PC, Furneaux RH, Kicska G, Xu Y, Grubmeyer C, Girvin ME, Schramm VL. Li CM, et al. Among authors: tyler pc. Nat Struct Biol. 1999 Jun;6(6):582-7. doi: 10.1038/9367. Nat Struct Biol. 1999. PMID: 10360365

5

The 2.0 A structure of human hypoxanthine-guanine phosphoribosyltransferase in complex with a transition-state analog inhibitor.

Shi W, Li CM, Tyler PC, Furneaux RH, Grubmeyer C, Schramm VL, Almo SC. Shi W, et al. Among authors: tyler pc. Nat Struct Biol. 1999 Jun;6(6):588-93. doi: 10.1038/9376. Nat Struct Biol. 1999. PMID: 10360366

6

The 2.0 A structure of malarial purine phosphoribosyltransferase in complex with a transition-state analogue inhibitor.

Shi W, Li CM, Tyler PC, Furneaux RH, Cahill SM, Girvin ME, Grubmeyer C, Schramm VL, Almo SC. Shi W, et al. Among authors: tyler pc. Biochemistry. 1999 Aug 3;38(31):9872-80. doi: 10.1021/bi990664p. Biochemistry. 1999. PMID: 10433693

7

Iminoribitol transition state analogue inhibitors of protozoan nucleoside hydrolases.

Miles RW, Tyler PC, Evans GB, Furneaux RH, Parkin DW, Schramm VL. Miles RW, et al. Among authors: tyler pc. Biochemistry. 1999 Oct 5;38(40):13147-54. doi: 10.1021/bi990829u. Biochemistry. 1999. PMID: 10529186

8

Transition state analogue inhibitors of protozoan nucleoside hydrolases.

Furneaux RH, Schramm VL, Tyler PC. Furneaux RH, et al. Among authors: tyler pc. Bioorg Med Chem. 1999 Nov;7(11):2599-606. doi: 10.1016/s0968-0896(99)00210-2. Bioorg Med Chem. 1999. PMID: 10632070

9

Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,).

Shi W, Munagala NR, Wang CC, Li CM, Tyler PC, Furneaux RH, Grubmeyer C, Schramm VL, Almo SC. Shi W, et al. Among authors: tyler pc. Biochemistry. 2000 Jun 13;39(23):6781-90. doi: 10.1021/bi000128t. Biochemistry. 2000. PMID: 10841757

10

Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.

Fedorov A, Shi W, Kicska G, Fedorov E, Tyler PC, Furneaux RH, Hanson JC, Gainsford GJ, Larese JZ, Schramm VL, Almo SC. Fedorov A, et al. Among authors: tyler pc. Biochemistry. 2001 Jan 30;40(4):853-60. doi: 10.1021/bi002499f. Biochemistry. 2001. PMID: 11170405

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